In this interview, George Kunos, MD, PhD discusses the involvement of endocannabinoid system (ECS) in regulating addiction and reward. Dr. Kunos also describes the role of CB1 receptors in regulating body weight and metabolic control, and highlights the critical differences of blocking CB1 receptors in the periphery versus the brain. George Kunos, MD, PhD is the Scientific Director of the National Institute on Alcohol Abuse and Alcoholism at the National Institutes of Health From the 16th International Conference on Bioactive…
In this interview, George Kunos, MD, PhD discusses the involvement of endocannabinoid system (ECS) in regulating addiction and reward. Dr. Kunos also describes the role of CB1 receptors in regulating body weight and…
In this interview, Cecilia Hillard, PhD discusses endocannabinoid system (ECS) signaling in depressive disorders. Dr. Hillard describes the effect of exercise on the ECS, and how this may underpin some of the benefits of exercise in patients with depression and other mood disorders. Dr. Hillard discusses emerging results in patients with post-traumatic stress disorder (PTSD) which show a different picture, and ends with a discussion on what we know about the role that the endocannabinoid receptors (CB1 and CB2) play…
In this interview, Cecilia Hillard, PhD discusses endocannabinoid system (ECS) signaling in depressive disorders. Dr. Hillard describes the effect of exercise on the ECS, and how this may underpin some of the benefits…
by Kari Hamrick, PhD, RD and Elnaz Karimian-Azari, PhD Introduction Since 2016, the US Department of Health and Human Services has brought a new level of awareness to the opioid crisis in America by declaring it a nationwide Public Health Emergency.1 In the US, it is approximated that 2.5 million people have been diagnosed with an opioid use disorder (OUD), and 4 in 5 new heroin users started out misusing opioid prescription pain medication.2 As part of the efforts aimed…
by Kari Hamrick, PhD, RD and Elnaz Karimian-Azari, PhD Introduction Since 2016, the US Department of Health and Human Services has brought a new level of awareness to the opioid crisis in America…
Introduction The endocannabinoid system (ECS) is an important biological system that regulates and balances a wide range of physiological functions in the body.1 Research on the ECS has led to the identification of not only endocannabinoids such as anandamide (AEA) and 2-arachidonoylglycerol (2-AG), but also endocannabinoid-like lipid mediators such as palmitoylethanolamide (PEA). These endocannabinoid-like compounds often share the same metabolic pathways of endocannabinoids but lack binding affinity for the classical cannabinoid receptor type 1 and type 2 (CB1 and CB2).5…
Introduction The endocannabinoid system (ECS) is an important biological system that regulates and balances a wide range of physiological functions in the body.1 Research on the ECS has led to the identification of…
More than 300 years after farmers had begun growing hemp as a staple crop in the United States, the endocannabinoid system (ECS) was discovered in the 1990s by researchers studying bioactive compounds in the Cannabis sativa plant. Since that time, cannabinoid receptors have been discovered in many different areas of the human body, such as the brain, digestive tract, and immune system, to name a few. Research continues to reveal diverse physiological functions of the ECS, unique properties of endogenous (endocannabinoids) and…
More than 300 years after farmers had begun growing hemp as a staple crop in the United States, the endocannabinoid system (ECS) was discovered in the 1990s by researchers studying bioactive compounds in…
by Sara Gottfried, MD and Elnaz Karimian-Azari, PhD The endocannabinoid system is a fascinating network involved in regulating many physiological, homeostatic, and cognitive functions—including appetite, immune function, pain, metabolism and energy balance, stress response, anxiety, mood, fertility, pregnancy, pre- and postnatal development, memory, and neurogenesis, as well as the well-known pharmacological effects of cannabis.1,2 In our developing understanding of network medicine, it’s important as clinicians to understand that the endocannabinoid system plays a role far beyond getting high and impacts…
by Sara Gottfried, MD and Elnaz Karimian-Azari, PhD The endocannabinoid system is a fascinating network involved in regulating many physiological, homeostatic, and cognitive functions—including appetite, immune function, pain, metabolism and energy balance, stress…
More than 300 years after farmers had begun growing hemp as a staple crop in the United States, the endocannabinoid system (ECS) was discovered in the 1990s by researchers studying bioactive compounds in the Cannabis sativaplant. Since that time, cannabinoid receptors have been discovered in many different areas of the human body, such as the brain, digestive tract, and immune system, to name a few. Research continues to reveal diverse physiological functions of the ECS, unique properties of endogenous (endocannabinoids) and…
More than 300 years after farmers had begun growing hemp as a staple crop in the United States, the endocannabinoid system (ECS) was discovered in the 1990s by researchers studying bioactive compounds in…
Erik Lundquist, MD presents a Nutrition Masters Course on the endocannabinoid system (ECS), a critical homeostatic regulator in the body. Topics in this webinar include ECS research history, ECS-related compounds and terminology, diverse physiological functions of the ECS, endocannabinoid tone, clinical endocannabinoid deficiency (CED), and potential clinical strategies to support ECS function—including phytocannabinoid bioactives found in the cannabis plant (e.g., from hemp extract).
Erik Lundquist, MD presents a Nutrition Masters Course on the endocannabinoid system (ECS), a critical homeostatic regulator in the body. Topics in this webinar include ECS research history, ECS-related compounds and terminology, diverse…
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