by Kara Fitzgerald, ND It looks like pyroptosis, a novel form of inflammatory cell death, may be a cause of the increased virulence of COVID-19 (although it was seen in SARS-CoV-1, too). Pyroptosis initiates the upregulation of inflammasome NLRP31 via caspase-1 proteases in the canonical pathway. Other caspases can also upregulate the inflammasome initiated by … Continue reading A Few Additional Treatment Possibilities for COVID19 (SARS Cov-2) Addressing Furin-Like Cleavage and Pyroptosis (Caspase-1 Activation of Inflammasome NLRP3)