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The Role of Insulin in Balancing Sex Hormones

Filomena Trindade, MD, MPH outlines the importance of insulin and the effects it has on other hormones in the body

“The importance of insulin and its downstream effects on the other hormones has really been downplayed and not really understood.” – Filomena Trindade, MD, MPH, a leading hormone specialist

While hundreds of millions of dollars are spent annually to balance hormones through replacement therapy, practitioners may be failing to assess the hormone that makes the biggest difference. Filomena Trindade, MD, MPH is a leading expert on hormones, with surprising and critical research on insulin’s role in the hormonal symphony.

Filomena Trindade, MD, MPH, is a board-certified Family and Integrative physician specializing in nutrition and personalized medicine. In this episode, Dr. Trindade shares that while a great deal of time and money is spent on attempting to balance hormones through hormone replacement therapy (HRT), practitioners may be failing to assess the hormone that makes the biggest difference. Dr. Trindade offers surprising and critical research on insulin’s role in the hormonal symphony.  

In this podcast: 

04:28 Dr. Trindade talks about her view on anxiety and how it differs from what she was taught in medical school 

05:18 Dr. Trindade talks about the gut-brain axis and the influence of food 

08:10 Dr. Trindade discusses the benefit of probiotics and which foods she feels contribute to anxiety and addictive tendencies  

13:29 Dr. Trindade explains why the complexity of women’s hormones may contribute to higher rates of anxiety and describes insulin as a master regulator  

17:08 Drs. Gottfried and Trindade review their personalized medicine protocols for anxiety in perimenopause 

22:27 Dr. Trindade reviews her method for measuring insulin pathways 

24:27 Dr. Trindade discusses addiction and the negative effects of alcohol 

27:47 Dr. Trindade discusses the importance of methylation  

Access the Extensive Show Notes

Get detailed show notes on how the approaches discussed differ from the conventional standard of care and learn ways to put these ideas into practice. Show notes also provide a deeper dive into the subject through links to our guest, additional talks and blog posts, related research and studies, and much more.

Hosted by
Sara Gottfried, MD

Sara Gottfried, MD is a board-certified gynecologist and physician scientist. She graduated from Harvard Medical School and the Massachusetts Institute of Technology and completed residency at the University of California at San Francisco. Over the past two decades, Dr. Gottfried has seen more than 25,000 patients and specializes in identifying the underlying cause of her patients’ conditions to achieve true and lasting health transformations, not just symptom management.

Dr. Gottfried is a global keynote speaker who practices evidence-based integrative, precision, and Functional Medicine. She recently published a new book, Brain Body Diet, and has also authored three New York Times bestselling books: The Hormone Cure, The Hormone Reset Diet, and Younger.

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