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Articles, Digestive, Integrative, Naturopathic, Nutritionists

by Bianca Garilli, ND Inflammatory bowel disease (IBD) is characterized by chronic inflammation in the digestive tract and can be classifed into two main conditions: ulcerative colitis (UC) and Crohn’s disease (CD). Both of these debilitating diseases involve similar symptoms including bloody diarrhea, abdominal pain and cramping, fever, fatigue, and unintended weight loss.1 The two disease processes, although overlapping in many ways, differ in their pathophysiology:1-2 CD: This disease can affect any part of the gastrointestinal (GI) tract and is…

by Bianca Garilli, ND Inflammatory bowel disease (IBD) is characterized by chronic inflammation in the digestive tract and can be classifed into two main conditions: ulcerative colitis (UC) and Crohn’s disease (CD). Both…

Articles, Digestive, Foundational, Integrative, Naturopathic, Nutritionists

by Bianca Garilli, ND It is well known that gut dysbiosis impacts various aspects of human health, from cardiovascular disease to asthma.1 Bacterial composition in the digestive tract can be influenced by many aspects of daily life: stress levels, environmental exposures, and dietary habits, including alcohol consumption, to name a few.1-2 The literature also suggests that alcohol intake may play a role in the makeup of human oral microbiota through several mechanisms including direct cytotoxic effects on bacteria, changing the…

by Bianca Garilli, ND It is well known that gut dysbiosis impacts various aspects of human health, from cardiovascular disease to asthma.1 Bacterial composition in the digestive tract can be influenced by many…

Articles, Cardiometabolic, Digestive, Functional Medicine, Integrative, Naturopathic, Nutritionists, Obesity

by Ashley Jordan Ferira, PhD, RDN The digestive system begins in the mouth, which is home to 700+ unique species of bacteria.1 Recent research has shown that salivary2 and gastrointestinal (GI)3-4 microbiota possess diurnal rhythms; whether these daily patterns are a result of circadian biology and/or eating behaviors is unknown. The composition of one’s habitual diet has been shown to impact human GI microbiota, and emerging research suggests that eating frequency and timing of meals may also play a role,3-4…

by Ashley Jordan Ferira, PhD, RDN The digestive system begins in the mouth, which is home to 700+ unique species of bacteria.1 Recent research has shown that salivary2 and gastrointestinal (GI)3-4 microbiota possess…

Articles, Digestive, Functional Medicine, Integrative, Naturopathic, Nutritionists

by Lewis Chang, PhD Gut microbiota, a community of trillions of microorganisms living in the gastrointestinal tract, play an important role in health and disease in humans. A loss in species richness and diversity in the microbiota has been associated with many metabolic disorders and disease states.1 Nutrition can have a significant impact on the microbiota composition. The Mediterranean diet is known for its various health benefits.2 However, little is known on how the Mediterranean dietary pattern affects the composition…

by Lewis Chang, PhD Gut microbiota, a community of trillions of microorganisms living in the gastrointestinal tract, play an important role in health and disease in humans. A loss in species richness and…

Digestive, Functional Medicine, Integrative, Naturopathic, Nutritionists

Lactobacillus salivarius UCC118 is a well-characterized and evidence-based probiotic strain. A feeding study led by Fergus Shanahan, MD and his research group at the University College Cork was conducted in patients with ulcerative colitis. This pilot-scale, open-label study aimed to determine the ability of L. salivarius UCC118 to adhere to human enterocyte epithelial cells. The bacterial strain was administered to patients with ulcerative colitis at ~109 CFU/day for 12 days. Biopsy specimen analyses demonstrated that the ingested bacteria effectively adhered to…

Lactobacillus salivarius UCC118 is a well-characterized and evidence-based probiotic strain. A feeding study led by Fergus Shanahan, MD and his research group at the University College Cork was conducted in patients with ulcerative…

Digestive, Functional Medicine, Integrative, Naturopathic, Nutritionists, Publications

Small intestinal bacterial overgrowth (SIBO) has become a significant health problem seen in many clinical practices. The prevalence estimates for SIBO in patients with irritable bowel syndrome (IBS) range from 4-78% (higher prevalence in diarrhea-predominant IBS)1 and is thought to be almost as high in many other disorders of the digestive tract. Defined as an increase in the concentration of bacteria of more than 100,000 colony-forming units per mL in the small intestine, SIBO can lead to malabsorption and malnutrition that…

Small intestinal bacterial overgrowth (SIBO) has become a significant health problem seen in many clinical practices. The prevalence estimates for SIBO in patients with irritable bowel syndrome (IBS) range from 4-78% (higher prevalence in…

Blogs, Digestive, Functional Medicine, Integrative, Naturopathic, Nutritionists

by Vincent Pedre, MD Small intestinal bacterial overgrowth (SIBO) is a controversial diagnosis that can masquerade behind a variety of symptoms, not all of which involve the characteristic bloating, gas and abdominal pain. SIBO also manifests as rosacea,1 diarrhea, constipation, anxiety,2 depression, fatigue, and iron deficiency. The astute clinician needs to hold a high degree of suspicion because a patient with SIBO may not present with the classic symptoms. For example, a recent severe case I saw presented only with diarrhea. Definitions First…

by Vincent Pedre, MD Small intestinal bacterial overgrowth (SIBO) is a controversial diagnosis that can masquerade behind a variety of symptoms, not all of which involve the characteristic bloating, gas and abdominal pain. SIBO…

Articles, Digestive, Functional Medicine, Integrative, Naturopathic, Nutritionists

by Lewis Chang, PhD Clostridium difficile, or "C. diff", is a bacterium that can cause infection in at-risk individuals, triggering symptoms ranging from mild diarrhea to severe pseudomembranous colitis. Major risk factors for C. diff infection include depletion of protective gut microorganisms due to antibiotics use (e.g. fluoroquinolones), compromised immune system, age, healthcare environment, and certain medications. Hospitalized older individuals with recent antibiotic exposure and those admitted to long-term care facilities are particularly susceptible for C. diff infection.1 Two fluoroquinolone-resistant…

by Lewis Chang, PhD Clostridium difficile, or "C. diff", is a bacterium that can cause infection in at-risk individuals, triggering symptoms ranging from mild diarrhea to severe pseudomembranous colitis. Major risk factors for…

Blogs, Digestive, Integrative, Naturopathic, Nutritionists

by Christopher Moulton, PhD Pectin is a complex and heterogeneous aggregation of polysaccharides first isolated from plant matter in 1825 by French chemist and pharmacist Henri Bracconot.1 Pectin is the major constituent of all plant primary cell walls, contributing to the plant’s structural integrity and providing a barrier to the external environment. Consequently, pectin is a component of all omnivorous diets. Pectin is known to be a soluble, prebiotic fiber that bypasses human digestion in the small intestine, but is…

by Christopher Moulton, PhD Pectin is a complex and heterogeneous aggregation of polysaccharides first isolated from plant matter in 1825 by French chemist and pharmacist Henri Bracconot.1 Pectin is the major constituent of…

Articles, Digestive, Foundational, Functional Medicine, Integrative, Naturopathic, Nutritionists

by Bianca Garilli, ND In a single year, Clostridium difficile (C. difficile) is responsible for nearly 500,000 infections among patients in the US. Approximately 29,000 of these patients die within 30 days of initial diagnosis of the infection, and 15,000 of those deaths can be attributed directly to C. difficile infection (CDI). C. difficile is now the most common microbial cause of healthcare-associated infection in US hospitals, with excess health care costs in acute care facilities estimated to be $4.8…

by Bianca Garilli, ND In a single year, Clostridium difficile (C. difficile) is responsible for nearly 500,000 infections among patients in the US. Approximately 29,000 of these patients die within 30 days of…

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