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Specialized Pro-resolving Mediators (SPMs): Research Review

Inflammation is an immune response to insults like injuries, infections, or unhealthy dietary patterns. It is critical to control and resolve inflammation to prevent chronic inflammatory conditions. Specialized pro-resolving mediators (SPMs) are produced from long-chain polyunsaturated fats, especially EPA and DHA. The SPM Research Review examines the benefits of resolution-based nutrition and how SPMs, unique lipid mediators, play an indispensable role in switching an inflammatory response in the direction of resolution and homeostasis.

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