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Articles, Cardiometabolic, Foundational, Functional Medicine, Integrative

COVID-19 March 31, 2020 Update Keeping the immune system healthy is on most people’s minds during the current COVID-19 pandemic. According to epidemiological data, smoking increases susceptibility and severity of flu caused by the influenza virus.1 And experimental data have shown that cigarette smoke directly inhibits epithelial antiviral pathways and increases replication of influenza virus.2 There are also data showing higher mortality among smokers in the 2012 outbreak caused by a coronavirus known as MERS-CoV.3 However, as SARS-CoV-2 is a…

COVID-19 March 31, 2020 Update Keeping the immune system healthy is on most people’s minds during the current COVID-19 pandemic. According to epidemiological data, smoking increases susceptibility and severity of flu caused by…

Blogs, Cardiometabolic, Foundational, Functional Medicine

by Kara Fitzgerald, ND It looks like pyroptosis, a novel form of inflammatory cell death, may be a cause of the increased virulence of COVID-19 (although it was seen in SARS-CoV-1, too). Pyroptosis initiates the upregulation of inflammasome NLRP31 via caspase-1 proteases in the canonical pathway. Other caspases can also upregulate the inflammasome initiated by a variety of triggers. The end results of NLRP3 upregulation include IL-1β and IL-18 production and cell death. In COVID-19 patients, higher serum IL-1β (a…

by Kara Fitzgerald, ND It looks like pyroptosis, a novel form of inflammatory cell death, may be a cause of the increased virulence of COVID-19 (although it was seen in SARS-CoV-1, too). Pyroptosis…

Blogs, Cardiometabolic, Functional Medicine

by Lewis Chang, PhD 1 . What was observed among patients with COVID-19 infection? According to three recently published studies, the most common comorbidities in patients with COVID-19 are hypertension (high blood pressure) and diabetes; roughly 20-30% of them had hypertension, and 6-22% of them had diabetes.1-3 There are other comorbidities reported, such as coronary heart disease and cerebrovascular disease. But hypertension and diabetes appear to be the most common, at least based on currently available data. 2.  Do scientists…

by Lewis Chang, PhD 1 . What was observed among patients with COVID-19 infection? According to three recently published studies, the most common comorbidities in patients with COVID-19 are hypertension (high blood pressure)…

Blogs, Cardiometabolic, Functional Medicine

by Mark Houston, MD and Sara Gottfried, MD Abstract. Cardiovascular disease, the leading cause of death in the United States, is not a single disease. It encompasses three different pathophysiological processes that involve the heart or the blood vessels. When considering whether omega-3 fatty acids have any benefit for our cardiovascular system, there is an enormous amount of misinformation in the news and reputable medical journals. Several articles state that omega-3 fatty acids have no role in cardiovascular disease, but…

by Mark Houston, MD and Sara Gottfried, MD Abstract. Cardiovascular disease, the leading cause of death in the United States, is not a single disease. It encompasses three different pathophysiological processes that involve…

Studies show that 50-70% of men have their first heart attack before they have any chest pain.  There are two issues with the traditional treatment of LDL cholesterol. First, many people experience adverse effects with statin therapy, requiring alternative approaches via diet and supplements to get their LDL cholesterol levels under control. The second issue is LDL cholesterol evaluation. We need to be looking at LDL particle number and size as well as whether or not it’s been modified. LDL…

Studies show that 50-70% of men have their first heart attack before they have any chest pain.  There are two issues with the traditional treatment of LDL cholesterol. First, many people experience adverse…

Mark Houston, MD, MS, FAHA, FASH, DABC; Internist & Cardiovascular Specialist; Director, Hypertension Institute and Vascular Biology HDL cholesterol plays vital roles in lipid biology and coronary heart disease pathophysiology. The main function of HDL is to scavenge for and carry LDL cholesterol away from the arteries and back to the liver, for redistribution, metabolism, and excretion. A high HDL measurement was previously thought to represent high reverse cholesterol transport, conferring heart-protective benefits for patients. But newer research indicates a…

Mark Houston, MD, MS, FAHA, FASH, DABC; Internist & Cardiovascular Specialist; Director, Hypertension Institute and Vascular Biology HDL cholesterol plays vital roles in lipid biology and coronary heart disease pathophysiology. The main function…

Cardiometabolic, Functional Medicine, Video

Understand components and mechanisms of HDL particles, reverse cholesterol transport,  and how to treat dysfunctional HDL.  

Understand components and mechanisms of HDL particles, reverse cholesterol transport,  and how to treat dysfunctional HDL.  

Cardiometabolic, Nutritionists, Pulse Patrol

Host: Deanna Minich, PhD Guest: Ali Miller, RD "One person’s superfood can be another’s kryptonite.” – Ali Miller, RD In this discussion, Ali Miller, RD, and Deanna Minich, PhD explore all things food and mood. Their conversations provides an overview of the gut-brain axis and the role that the gut and microbiome play in mood. Ali opens the discussion by describing her personal experience with anxiety. Her unexplained symptoms helped her realize the impact stress could have on the HPA-axis, and…

Host: Deanna Minich, PhD Guest: Ali Miller, RD "One person’s superfood can be another’s kryptonite.” – Ali Miller, RD In this discussion, Ali Miller, RD, and Deanna Minich, PhD explore all things food and…

Cardiometabolic, Functional Medicine, Podcasts, Video

Get the inside scoop from Sara Gottfried, MD on the latest research on intermittent fasting, time-restricted eating, and the relationship to your metabolism and detoxification abilities. Explore several periodic fasting regimens and how to implement them.

Get the inside scoop from Sara Gottfried, MD on the latest research on intermittent fasting, time-restricted eating, and the relationship to your metabolism and detoxification abilities. Explore several periodic fasting regimens and how…

Blogs, Cardiometabolic, Foundational, Functional Medicine, Integrative, Naturopathic, Nutritionists

by Mark Houston, MD and Sara Gottfried, MD The top five cardiovascular risk factors are hypertension, diabetes mellitus, dyslipidemia, obesity and smoking. Numerous clinical trials suggest that we have reached  a limit in our ability to lower the incidence of coronary heart disease with conventional diagnostic evaluation, prevention and treatment strategies for these risk factors. About 80% of heart disease (heart attacks, angina, coronary heart disease and congestive heart failure) can be prevented by optimal nutrition, optimal exercise, optimal weight…

by Mark Houston, MD and Sara Gottfried, MD The top five cardiovascular risk factors are hypertension, diabetes mellitus, dyslipidemia, obesity and smoking. Numerous clinical trials suggest that we have reached  a limit in…

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