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In the ERr731® and Menopause Research Review, the natural transition period of perimenopause and associated physiological changes are examined, with a focused look at vasomotor symptoms like hot flushes. Pharmacologic and natural treatments for menopausal symptoms are detailed, including the safety and efficacy research that spans 30+ years for a unique phytoestrogen extract from the roots of Siberian rhubarb (Rheum rhaponticum L.) called ERr731®, a non-hormonal therapy. View the Research Review to learn more

In the ERr731® and Menopause Research Review, the natural transition period of perimenopause and associated physiological changes are examined, with a focused look at vasomotor symptoms like hot flushes. Pharmacologic and natural treatments…

A growing body of literature suggests an association between toxicant exposure and the etiology of a number of chronic conditions. Optimizing the body's ability to manage and excrete toxins is essential for health. Minimizing toxin exposure is only one part of a successful strategy to decrease susceptibility to toxicity-related conditions. The Detoxification and Health Research Review explores toxin classes, their health impact, and how low-allergy-potential, targeted nutrition can support balanced detoxification and health throughout life. View the Research Review to…

A growing body of literature suggests an association between toxicant exposure and the etiology of a number of chronic conditions. Optimizing the body's ability to manage and excrete toxins is essential for health.…

Human milk vs. other mammal milk is unique for its abundance of oligosaccharides, which are unique carbohydrate polymers. The Human Milk Oligosaccharides (HMO) Research Review examines the structure and functions of HMOs, which act as prebiotics, promoting the growth of beneficial gut microbiota and the production of short-chain fatty acids that create an environment that discourages the growth of potential pathogens. HMOs also serve as antiadhesive antimicrobials, thus reducing the risk of infections, and have also been shown to modulate…

Human milk vs. other mammal milk is unique for its abundance of oligosaccharides, which are unique carbohydrate polymers. The Human Milk Oligosaccharides (HMO) Research Review examines the structure and functions of HMOs, which…

The phytochemical xanthohumol is a flavonoid found in the flowers of hops (Humulus lupulus L.), a plant that has long been used in medicine for various applications and also in brewing of beer. The Xanthohumol Research Review explores the sources, bioavailability, and known biological properties and effects of xanthohumol, with a focus on its anti-inflammatory and antioxidant properties via kinase modulation, which have implications for metabolic pathways related to chronic conditions. View the Research Review to learn more

The phytochemical xanthohumol is a flavonoid found in the flowers of hops (Humulus lupulus L.), a plant that has long been used in medicine for various applications and also in brewing of beer.…

Probiotics from the Lactobacilli and Bifidobacteria genera are some of the most commonly studied and used. Two specific probiotic strains, Lactobacillus rhamnosus GG (LGG®)* and Bifidobacterium animalis subsp. lactis BB-12 (BB-12®)*, have been extensively researched for safety and efficacy, particularly in the pediatric population. The LGG® and BB-12® Research Review examines the clinical evidence for these two probiotic strains as a primary preventive and management strategy for many of the most common infectious diseases and skin disorders affecting children. View…

Probiotics from the Lactobacilli and Bifidobacteria genera are some of the most commonly studied and used. Two specific probiotic strains, Lactobacillus rhamnosus GG (LGG®)* and Bifidobacterium animalis subsp. lactis BB-12 (BB-12®)*, have been…

Inflammation is an immune response to insults like injuries, infections, or unhealthy dietary patterns. It is critical to control and resolve inflammation to prevent chronic inflammatory conditions. Specialized pro-resolving mediators (SPMs) are produced from long-chain polyunsaturated fats, especially EPA and DHA. The SPM Research Review examines the benefits of resolution-based nutrition and how SPMs, unique lipid mediators, play an indispensable role in switching an inflammatory response in the direction of resolution and homeostasis. View the Research Review to learn more

Inflammation is an immune response to insults like injuries, infections, or unhealthy dietary patterns. It is critical to control and resolve inflammation to prevent chronic inflammatory conditions. Specialized pro-resolving mediators (SPMs) are produced…

Oral digestive enzymes are a useful adjunctive therapy for individuals avoiding dietary gluten as a result of gluten sensitivity, intolerance or celiac disease. Aspergillus niger prolyl endoprotease (AN-PEP) is an extensively studied, gluten-digesting enzyme that is naturally occurring from the A. niger microorganism. It is resistant to the pH extremes and endogenous digestive enzymes found in the gastrointestinal tract. The AN-PEP Research Review examines the purpose, origin, actions (i.e., breaking down gluten peptides and intact gluten proteins), and clinical study…

Oral digestive enzymes are a useful adjunctive therapy for individuals avoiding dietary gluten as a result of gluten sensitivity, intolerance or celiac disease. Aspergillus niger prolyl endoprotease (AN-PEP) is an extensively studied, gluten-digesting…

Consumption of fruits, vegetables, herbs, and spices is associated with reduced risk of many chronic diseases. Only in the past few decades has research revealed that plants produce a wide variety of phytochemicals, commonly referred to as phytonutrients, which play unique roles in human health. The Phytonutrients Research Review explores plant-based dietary patterns, with a focus on the Mediterranean diet, followed by a detailed discussion of the health benefits of various phytonutrients and their associated biological mechanisms. View the Research…

Consumption of fruits, vegetables, herbs, and spices is associated with reduced risk of many chronic diseases. Only in the past few decades has research revealed that plants produce a wide variety of phytochemicals,…

Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are long-chain polyunsaturated omega-3 fatty acids derived from marine sources, such as oily fish and fish oil or algal products. EPA and DHA act in the body via cell membrane incorporation, specific cellular receptors, and the generation of critical down-stream lipid mediators such as eicosanoids and specialized pro-resolving mediators (SPMs). The EPA & DHA Research Review covers the sources, recommendations, functions, and various areas of clinical support for EPA and DHA, including cardiovascular,…

Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are long-chain polyunsaturated omega-3 fatty acids derived from marine sources, such as oily fish and fish oil or algal products. EPA and DHA act in the…

Positive associations have been found between rising obesity/body mass index (BMI) levels and Clostridium difficile infections (CDI) rates. Additionally, recent studies point to changes in the human microbiome as a potential mechanism for increased rates of CDI, along with the obvious increase in CDI prevalence associated with the use of proton pump inhibitors (PPIs) for gastroesophageal reflux disease (GERD), a common occurrence in those with elevated BMI. Download the Clinical Review to learn more

Positive associations have been found between rising obesity/body mass index (BMI) levels and Clostridium difficile infections (CDI) rates. Additionally, recent studies point to changes in the human microbiome as a potential mechanism for increased rates of…

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