by Lewis Chang, PhD Not all heroes are muscle-bound and wear capes. There is a tiny, almost invisible, hero that lives in our gut and promotes our health and wellbeing. Its name, Akkermansia muciniphila, may be a mouthful, but it’s time to get to know this hero better, as its health-promoting effects have earned it the reputation as a next-generation beneficial bacteria.1 Gut health is intricately connected to human health in ways that surprise us. Our gut is home to…

We have compiled our most viewed blogs, webinars, and clinical tools on metabolic detoxification to help you keep up with the latest research on this topic that will enable you to help your patients’ live healthier, happier lives.

Angela Kelly, MA and Michael Stanclift, ND This is the last installment of a three-part series on bacterial vaginosis (BV). In part one, we discussed a healthy vaginal microbiome, symptoms, and diagnostic criteria. In part two , we highlighted the risk factors that contribute to BV, the health impacts it can cause, and conventional antimicrobial treatments, along with their propensity for resistance. As we saw in part two , conventional antimicrobials often only temporarily resolve BV, and contribute to antibiotic resistance. For…

Angela Kelly, MA and Michael Stanclift, ND This is part two in a three-part series about bacterial vaginosis (BV). In part one we discussed a healthy vaginal microbiome, BV’s characteristics, and diagnostic criteria. In this section, we’ll explore risk factors for developing BV, the health impacts of it, and current conventional therapies. BV risk factors While the precise causes of BV are still being investigated, researchers have discovered the following risk factors that can contribute to its development: Having a sexual…

Angela Kelly, MA and Michael Stanclift, ND In part one of this three-part series, we’ll discuss a healthy vaginal microbiome, symptoms, and the diagnostic criteria of bacterial vaginosis (BV). A healthy vaginal microbiome The vaginal microbiome is the lesser-known heroine of the body's microbiomes and the first line of defense against pathogens that can cause infections.1-5 Like the gut microbiome, the vaginal microbiome is seeded from mother to daughter and the surrounding environment within 24 hours of birth.6-7Hormonal fluctuations related…

Patients with obesity suffer from chronic, low-grade inflammation.1 That’s partly due to dysfunctions in the ability to endogenously create specialized pro-resolving mediators (SPMs).1 SPMs communicate with immune cells, telling them the inflammatory process is no longer needed and to finish the job.2 However, in many conditions, including obesity, the capability to send these potent signaling molecules can diminish, and so too can their effects.1-3 As a result, inflammation smolders and further perpetuates a vast array of associated conditions such as…

Menopause can be a serious disruption to a woman’s life. For decades, women and their doctors have turned to hormone replacement and nonhormonal therapies to seek relief. Many women prefer not to take hormones, or for various reasons hormones present a specific health risk, taking them off the table for therapy. A plant extract (ERr 731), made from Siberian rhubarb (Rheum rhaponticum) has been in use for treating menopause in Europe since the 1990s and is now gaining momentum in…

Hormone replacement therapy (HRT) is a mainstay for treating menopause, but more and more women are searching for non-hormonal therapies. An extract from Siberian Rhubarb (latin name Rheum rhaponticum) has been in use treating menopause for decades, and is now gaining popularity in more markets worldwide. Recently (2021) another clinical trial demonstrated the efficacy and safety of this extract, ERr-731, in treating menopause in Indian women.1 In this Indian trial researchers found a 4 mg once daily dose led to…

by Michael Stanclift, ND Patients with digestive problems aren’t always taken seriously by primary care providers. Often cases are dismissed with the nebulous diagnosis of irritable bowel syndrome (IBS), when the problem hasn’t been adequately worked up and given the proper attention. A recent study in Scientific Reports found that up to half of patients diagnosed with IBS also have a treatable and consequential condition called small intestinal bacterial overgrowth (SIBO). SIBO in and of itself has many underlying causes, and…

Metabolic detoxification (detox)—or biotransformation—is a physiological function that removes toxic substances of endogenous or exogenous origin from the body. Because the function and regulation of this process varies from person to person, different people can have a different sensitivity to toxic substances and their effects on the development of a variety of diseases such as liver conditions, fertility problems, and cancer. Along with sex, age, and lifestyle, genetics play an important role in this variability. But do we actually know…