In Q&A Part 3, Dominic D’Agostino, PhD explains a conundrum: the evidence basis and clinical benefits of the ketogenic diet for certain chronic disease states are well known, however, there are many individuals who are unable or unwilling to implement a ketogenic diet. To address this issue, Dr. D’Agostino and others are researching the impact of exogenous ketone supplementation on raising ketone levels in the body. Dr. D’Agostino shares the latest research in this area and provides his expert perspective on the efficacy and clinical utility of medium-chain triglycerides (MCTs), ketone salts, and ketone esters in achieving and maintaining a state of ketosis.
Originally aired September 27, 2018
Dominic D’Agostino, PhD is a neuroscience, molecular pharmacology, and physiology researcher with a vast array of professional, academic, and personal pursuits and achievements. As a tenured Associate Professor at the University of South Florida, Dr. D’Agostino teaches students at the Morsani College of Medicine and the Department of Molecular Pharmacology and Physiology, with a focus on neuropharmacology, medical biochemistry, physiology, cell metabolism, and signaling.
Dr. D’Agostino’s laboratory develops and tests metabolic-based strategies for targeting CNS oxygen toxicity (seizures), epilepsy, neurodegenerative diseases, and cancer. The main focus of his lab over the last decade has been understanding the anticonvulsant and neuroprotective mechanism of the ketogenic diet and ketone metabolite supplementation. Dr. D’Agostino is also a Research Scientist at the Florida Institute for Human and Machine Cognition (IHMC), assisting with environmental medicine research efforts to optimize the safety, health, and resilience of the warfighter and astronaut. Dr. D’Agostino was a research investigator and crew member on NASA’s Extreme Environment Mission Operation (NEEMO 22). His research is supported by the Office of Naval Research (ONR), Department of Defense (DoD), private sources, and foundations.
Dr. D’Agostino received his PhD in Physiology and Neuroscience from Rutgers University and Robert Wood Johnson Medical School and completed postdoctoral fellowships in molecular pharmacology and physiology at University of South Florida and in neuroscience at Boonshoft School of Medicine at Wright State University.
Watch a preview of the video series below.