In this MAPS talk, Dr. Dominic D’Agostino examines the role of the ketogenic diet in metabolic health optimization. We know that metabolic health correlates with overall health in the body, so by optimizing metabolic health, defined by a set of biomarkers that reliably predict the physiological and metabolic state, we can potentially help delay the onset of many age-related chronic diseases. Dr. D’Agostino explains how the ketogenic diet may help manage many of these conditions, such as type 2 diabetes and Alzheimer’s disease.
Originally aired November 1, 2018
Dominic D’Agostino, PhD is a neuroscience, molecular pharmacology, and physiology researcher with a vast array of professional, academic, and personal pursuits and achievements. As a tenured Associate Professor at the University of South Florida, Dr. D’Agostino teaches students at the Morsani College of Medicine and the Department of Molecular Pharmacology and Physiology, with a focus on neuropharmacology, medical biochemistry, physiology, cell metabolism, and signaling.
Dr. D’Agostino’s laboratory develops and tests metabolic-based strategies for targeting CNS oxygen toxicity (seizures), epilepsy, neurodegenerative diseases, and cancer. The main focus of his lab over the last decade has been understanding the anticonvulsant and neuroprotective mechanism of the ketogenic diet and ketone metabolite supplementation. Dr. D’Agostino is also a Research Scientist at the Florida Institute for Human and Machine Cognition (IHMC), assisting with environmental medicine research efforts to optimize the safety, health, and resilience of the warfighter and astronaut. Dr. D’Agostino was a research investigator and crew member on NASA’s Extreme Environment Mission Operation (NEEMO 22). His research is supported by the Office of Naval Research (ONR), Department of Defense (DoD), private sources, and foundations.
Dr. D’Agostino received his PhD in Physiology and Neuroscience from Rutgers University and Robert Wood Johnson Medical School and completed postdoctoral fellowships in molecular pharmacology and physiology at University of South Florida and in neuroscience at Boonshoft School of Medicine at Wright State University.