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Can We Predict, Detect, and Mitigate Disease Through Epigenetic Approaches?

The differences between Florence Comite, MD and her twin sister sparked a curiosity about variations in gene expression

“Mother Nature gives us all these gifts, and then Father Time starts stripping them away.” – Florence Comite, MD, a leader in precision medicine

Florence Comite, MD, a leading force in precision medicine, has the data on why Father Time strips away the genetic gifts Mother Nature gives us and what we can do about it.

Dr. Florence Comite is a clinician-scientist and innovator in the field of Precision Medicine, internationally known for her expertise in leveraging N-of-1 data to detect, predict, and reverse disorders of aging for optimal health and vitality. In 2005, Dr. Comite founded the Center for Precision Medicine & Health in New York City, where she established a clinically proven, academic approach to personalized health care, structured as a clinical trial. By integrating and interpreting genomic, metabolomic, phenotypic, and digital health data, the Center provides predictive analysis and actionable guidance for the individual patient. Dr. Comite’s global clientele spans the population, from forward-thinking physicians to jet-setting executives, and self-quantifying millennials.

Dr. Comite’s startup QUANTIOME™ scales her unique approach to personalized, actionable Precision Medicine as a digital application.

Dr. Comite is a graduate of Yale School of Medicine where she was a faculty member for 25 years, with a triple appointment in Endocrinology (Internal Medicine and Pediatrics) and Reproductive Endocrinology (Gynecology and Andrology). Dr. Comite trained at the National Institute of Child Health and Human Development, National Institutes of Health (NIH). In 1992, Dr. Comite founded Women’s Health at Yale.

Dr. Comite has published original research in numerous clinical journals and contributes regularly to editorial publications. She is the Amazon bestselling author of Keep It Up: The Power of Precision Medicine to Conquer Low T and Revitalize Your Life!

In this podcast:

02:12 Dr. Comite shares her story

03:29 Dr. Comite describes why she changed her approach to medicine and how the data supports that approach

05:04 Dr. Comite explains how her experience of being an identical twin triggered an interest in genomics

06:04 Dr. Comite describes the appeal of N-of-1 trials

08:55 Dr. Comite defines precision medicine

11:10 Dr. Comite discusses her medical model

12:40 Dr. Comite shares her message of hope for the future of medicine


Hosted by
Sara Gottfried, MD

Sara Gottfried, MD is a board-certified gynecologist and physician scientist. She graduated from Harvard Medical School and the Massachusetts Institute of Technology and completed residency at the University of California at San Francisco. Over the past two decades, Dr. Gottfried has seen more than 25,000 patients and specializes in identifying the underlying cause of her patients’ conditions to achieve true and lasting health transformations, not just symptom management.

Dr. Gottfried is a global keynote speaker who practices evidence-based integrative, precision, and Functional Medicine. She recently published a new book, Brain Body Diet, and has also authored three New York Times bestselling books: The Hormone Cure, The Hormone Reset Diet, and Younger.

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