While SPMs offer an exciting opportunity to treat and manage the inflammation often associated with chronic disease, it is crucial to consider the correct amount of SPM for various clinical conditions.
In this short video with Dr. Charles Serhan of Harvard Medical School, MHICN inquires about the correct dose of SPM in humans. Dr. Serhan responds that the correct dosing levels have yet to be established fully. Questions that remain include: does gender play a role? Does age play a role? Do we need more SPMs as we age?
It is likely that more SPMs are needed as we age, based on a mouse model. In mice models, aged mice have less effective inflammation resolution response, as well as lower levels of SPMs in the body. Further research in humans is still needed.
13. Insights from the Metagenics Lifestyle Summit 2015: Charles Serhan, PhD