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Articles, Functional Medicine, Musculoskeletal

Most patients seeking pain relief rely on the following three families of drugs: opioids, gabapentinoids, and nonsteroidal anti-inflammatory agents (NSAIDs). These widely used drugs are associated with serious side effects.1 During the past decade there has been an increasing interest in cannabis-derived products for pain management with a better safety profile and adequate pain relief. However, we still know surprisingly little about the effectiveness of nonintoxicating cannabis-based products on pain—conventionally referred to as “industrial hemp.” A new preclinical study using…

Most patients seeking pain relief rely on the following three families of drugs: opioids, gabapentinoids, and nonsteroidal anti-inflammatory agents (NSAIDs). These widely used drugs are associated with serious side effects.1 During the past…

Articles, Digestive, Nutritionists

Prebiotics are types of food ingredients that are nondigestible by humans and broken down by human gut bacteria into compounds that are beneficial for humans. Human breast milk contains a rich source of prebiotics called “human milk oligosaccharides” or “HMOs,” which act as the very first prebiotics taken in by a nursing infant.1 Among the HMOs, 2’-fucosyllactose (2’-FL) is the most abundantly produced.2 The effect of 2’-FL was recently studied in adults with irritable bowel syndrome (IBS) and inflammatory bowel…

Prebiotics are types of food ingredients that are nondigestible by humans and broken down by human gut bacteria into compounds that are beneficial for humans. Human breast milk contains a rich source of…

Articles, Digestive, Nutritionists

Single-strain and multistrain probiotics can be beneficial for specific clinical applications.1,2 Potential advantages of multistrain probiotic supplements are a broader spectrum of health benefits (compared to intake of a single probiotic strain) and synergistic effects of the individual probiotic strains.2 Clinical trial results on a new, high colony-forming units (CFU) count combination of 8 strains of Lactobacillus and Bifidobacterium probiotics were recently published in Integrative Medicine: A Clinician’s Journal.3 The study evaluated the short-term impact of consumption of one capsule…

Single-strain and multistrain probiotics can be beneficial for specific clinical applications.1,2 Potential advantages of multistrain probiotic supplements are a broader spectrum of health benefits (compared to intake of a single probiotic strain) and…

Articles, Foundational, Functional Medicine

The ketogenic diet (KD) is a low-carbohydrate, high-fat, adequate-protein diet that has proven to be effective for the reversal of several chronic conditions including obesity, metabolic syndrome, and type-2 diabetes (T2DM) in trials of up to two years.1 However, the degree of therapeutic response to KD varies across individuals.2,3 For example, some KD dieters lose more weight than others, and, while most of them improve their blood lipids, so-called “high responders” experience abnormal increases in low-density lipoprotein cholesterol (LDL-C). Many…

The ketogenic diet (KD) is a low-carbohydrate, high-fat, adequate-protein diet that has proven to be effective for the reversal of several chronic conditions including obesity, metabolic syndrome, and type-2 diabetes (T2DM) in trials…

Articles, Functional Medicine

Chemicals used in food packaging that can lower antibody responses in humans will be phased out starting in 2021. JAMA reported on the FDA announcement that several manufacturing companies have agreed to a voluntary phase-out per- and poly-fluoroalkyl substances (PFAS), which are used to keep fats from soaking into paper and cardboard food packaging.1 These chemicals are immunotoxic to humans and animals, harming the immune system directly.2 Their effects range from a mild reduction in antibody response levels (measured from…

Chemicals used in food packaging that can lower antibody responses in humans will be phased out starting in 2021. JAMA reported on the FDA announcement that several manufacturing companies have agreed to a…

Articles, Foundational, Functional Medicine, Integrative, Nutritionists

COVID-19 April 6, 2020 Update On April 2nd, the number of COVID-19 cases reached 1 million worldwide. The US currently has over 300,000 reported cases, more than any other country in the world. Amid the uncertainty around the pandemic, the US is also learning so much more about the novel coronavirus. Epidemiologists and infectious disease experts recently published what they had learned based on existing data in JAMA Viewpoint. Below are some of the highlights.1 How does SARS-CoV-2 spread? The…

COVID-19 April 6, 2020 Update On April 2nd, the number of COVID-19 cases reached 1 million worldwide. The US currently has over 300,000 reported cases, more than any other country in the world.…

Articles, Cardiometabolic, Foundational, Functional Medicine, Integrative

COVID-19 April 2, 2020 Update Currently, the diagnosis of SARS-CoV-2 infection heavily relies on RT-PCR-based viral RNA detection method. Although the test has high sensitivity (i.e., true positive rate), there are challenges with the test that may cause delay of a confirmed diagnosis, thereby impacting timing of treatment and ability to control further spread of the virus. Here are some variables: Test sample collected at different stage of infection: The viral RNA test has high sensitivity in the early stage…

COVID-19 April 2, 2020 Update Currently, the diagnosis of SARS-CoV-2 infection heavily relies on RT-PCR-based viral RNA detection method. Although the test has high sensitivity (i.e., true positive rate), there are challenges with…

Articles, Cardiometabolic, Foundational, Functional Medicine, Integrative

COVID-19 March 31, 2020 Update Keeping the immune system healthy is on most people’s minds during the current COVID-19 pandemic. According to epidemiological data, smoking increases susceptibility and severity of flu caused by the influenza virus.1 And experimental data have shown that cigarette smoke directly inhibits epithelial antiviral pathways and increases replication of influenza virus.2 There are also data showing higher mortality among smokers in the 2012 outbreak caused by a coronavirus known as MERS-CoV.3 However, as SARS-CoV-2 is a…

COVID-19 March 31, 2020 Update Keeping the immune system healthy is on most people’s minds during the current COVID-19 pandemic. According to epidemiological data, smoking increases susceptibility and severity of flu caused by…

Articles, Foundational, Functional Medicine, Integrative, Naturopathic

COVID-19 March 30, 2020 Update Most of us are exercising physical distancing, avoiding running unnecessary errands, and other control measures in order to minimize person-to-person transmission of COVID-19. The goal is to “flatten the curve,” to delay the rapid spread of the novel coronavirus, thereby reducing the surge of illnesses in a very short time and allowing the healthcare system to breathe, to accommodate, to provide proper patient care. However, how long can (or should) schools remain closed, businesses shut,…

COVID-19 March 30, 2020 Update Most of us are exercising physical distancing, avoiding running unnecessary errands, and other control measures in order to minimize person-to-person transmission of COVID-19. The goal is to “flatten…

Articles, Foundational, Functional Medicine

(Coronavirus) COVID-19 March 27, 2020 Update Two Research Letters published online March 26th in the JAMA described 3 cases of possible vertical transmission.1,2 In the first report,1 an infant girl was delivered by cesarean in a negative-pressure isolation room. She had no symptoms and was immediately quarantined. The mother with COVID-19 wore an N95 mask and did not hold the infant. Test results 2 hours after birth showed higher IgM antibody level. Because IgM antibodies do not usually appear until…

(Coronavirus) COVID-19 March 27, 2020 Update Two Research Letters published online March 26th in the JAMA described 3 cases of possible vertical transmission.1,2 In the first report,1 an infant girl was delivered by…

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