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A New Perspective on Alzheimer’s Disease

Lisa Mosconi, PhD posits that over 90% of Alzheimer’s disease may be avoided by the choices we make today

“No more than 6 or 7% of all families affected by Alzheimer’s have genetic mutations that cause the disease.” – Lisa Mosconi, PhD
Discover what choices we make today can prevent Alzheimer’s disease in our future on this episode of The Practice.

Lisa Mosconi, PhD

Lisa Mosconi, PhD, a brilliant neuroscientist, reveals the latest research on Alzheimer’s disease and on the disproportionate rate that women are affected by Alzheimer’s, depression, and anxiety. Get the surprising new estimates regarding the role of genetics, as well as a comprehensive list of what to watch for now and what testing to explore.

Dr. Lisa Mosconi, PhD, is the Director of the Women’s Brain Initiative and Associate Director of the Alzheimer’s Prevention Clinic at Weill Cornell Medical College (WCMC)/NewYork-Presbyterian Hospital, where she serves as an Associate Professor of Neuroscience in Neurology and Radiology. She is also an adjunct faculty member at the Department of Psychiatry at New York University (NYU) School of Medicine, and t the Department of Nutrition at NYU Steinhardt School of Nutrition and Public Health.

In this podcast:

06:30 Dr. Mosconi dives into what we know and what we don’t know about Alzheimer’s disease and the importance of lifestyle in prevention

09:40 Dr. Mosconi reviews the assessment process involved in her research on Alzheimer’s

16:03 Dr. Mosconi discusses her overall findings related to women’s brains during menopause

19:59 Dr. Mosconi walks us through the differences in PET scan images taken during premenopause, perimenopause, and postmenopause

25:30 Dr. Mosconi discusses the theory of Alzheimer’s as an immune response

28:55 Dr. Mosconi suggests metabolic changes occur long before atrophy and are potentially reversible

31:45 Dr. Mosconi provides solutions for the prevention and management of cerebral hypometabolism

41:00 Dr. Mosconi discusses the impact sleep and stress have on brain health and sex differences in these areas

44:04 Dr. Mosconi speaks to the confusion around hormone replacement therapy (HRT)


Hosted by
Sara Gottfried, MD

Sara Gottfried, MD is a board-certified gynecologist and physician scientist. She graduated from Harvard Medical School and the Massachusetts Institute of Technology and completed residency at the University of California at San Francisco. Over the past two decades, Dr. Gottfried has seen more than 25,000 patients and specializes in identifying the underlying cause of her patients’ conditions to achieve true and lasting health transformations, not just symptom management.

Dr. Gottfried is a global keynote speaker who practices evidence-based integrative, precision, and Functional Medicine. She recently published a new book, Brain Body Diet, and has also authored three New York Times bestselling books: The Hormone Cure, The Hormone Reset Diet, and Younger.

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