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Markers to Assess the Efficacy of SPMs?

 

Specialized Pro-Resolving Mediators (SPMs) offer an exciting opportunity to treat and manage the inflammation often associated with chronic disease. In this short video, Metagenics Institute asks Dr. Charles Serhan of Harvard Medical School about some parameters or markers that can be used to assess the efficacy of SPMs.

Dr. Serhan responds that indices have been created to measure SPMs. Current tools include assessing pre- and post- levels of SPMs in blood, as well as the functional increase related to certain pathophysiologies.

While there is no panacea for all inflammatory-based diseases, case-by-case clinical trials are necessary and direct measurements will be helpful. Identifying dosage, route of administration, and specific type of SPM will be necessary.

5. Insights from the Metagenics Lifestyle Summit 2015: Charles Serhan, PhD

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