In this interview, Dipak Panigraphy, MD discusses cytokine storms in both COVID-19 and cancer patients, emphasizing their potential to disrupt resolution of inflammation and contribute to unfavorable clinical outcomes. Dr. Panigraphy discusses how standard cancer treatments, including surgery and chemotherapy, may trigger cytokine storms, facilitating the spread of cancer in some patients. Lastly, he discusses his latest research, demonstrating the efficacy of specific specialized pro-resolving mediators (SPMs) molecules in promoting inflammation resolution and preventing treatment-induced metastasis in multiple preclinical cancer…

We have compiled our most viewed blogs, webinars, and clinical tools on metabolic detoxification to help you keep up with the latest research on this topic that will enable you to help your patients’ live healthier, happier lives.

There is a growing body of research on the use of specialized pro-resolving mediators (SPMs) as a key therapy for many different conditions.

Our protective skin is constantly facing environmental insult such as solar UV radiation. Oxidative stress can damage skin components and accelerate skin aging. Learn how we may support our skin by boosting skin’s antioxidant capacity via a phytonutrient-rich diet.

In this brief hallway chat, Mimi Guarneri, MD addresses how to manage stress and aging using integrative medicine and lifestyle approaches. Dr. Guarneri also answers a few questions on how to personalize use of phytonutrients (e.g., quercetin) and bioactives (e.g., omega-3) for gut and heart health, with the proper use of biomarkers and elimination diet protocols. Download the transcript          

Gastroenterologist Dr. Marvin Singh describes his philosophy on bringing patients back to health. Understand that the gut is the tattletale of the body; having symptoms in the gut does not always mean it is a gut problem. Dr. Singh discusses the importance of assessing the anti-inflammatory capacity of the microbiome, understanding the diagnostics, remembering the lifestyle basics, and talking to the patients. By “dialing things back a bit,” we better see all the factors that are happening in a patient…

In this hallway chat, Ashley Koff, RD, addresses the gut connection to our skin health. She also demystifies the role of chocolate, dairy and sugar on skin issues, and provides practical tips on foods to avoid for acne and the scientific reason behind it.

In this interview, Joan Claria, PhD discusses the discovery that a resolution deficit occurs in obesity. Dr. Claria outlines the important role that specialized pro-resolving mediators (SPMs) play in adipose tissue and metabolic health, and outlines future potential for SPM-based therapies in the management of fatty liver disease. Joan Claria, PhD is Professor at the Department of Biomedical Sciences at the School of Medicine of the University of Barcelona, Spain From the 16th International Conference on Bioactive Lipids in Cancer,…

In this interview, Dipak Panigrahy, MD discusses the emerging impact of specialized pro-resolving mediators (SPMs) on tumor size and growth, highlighting his work with several preclinical models including pancreatic cancer and breast cancer.  Dr. Panigrahy outlines the reduction in metastases seen in preclinical cancer models, including pancreatic cancer, following treatments with various SPMs. Finally, Dr Panigrahy describes results in preclinical models showing that SPM treatment helps to clear tumor debris caused by standard of care cancer treatments. Dipak Panigrahy, MD,…

In this interview, Bruce Levy, MD describes the loss of inflammatory ‘breaking signals’ in the lung of patients with asthma. Dr. Levy highlights how this defective resolution phenotype negatively impacts both adaptive and innate immune responses in individuals with asthma, leaving them more vulnerable to infection. Bruce Levy, MD is the Chief of the Division of Pulmonary and Critical Care Medicine at Brigham and Women's Hospital, MA and Parker B. Francis Professor at Harvard Medical School From the 16th International…