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by Anu Desai, PhD Messenger RNA (mRNA) is a single-stranded molecule of genetic code found in all living cells. As a chemical intermediary, mRNA carries instructions from deoxyribonucleic acid (DNA) in our chromosomes to cellular machinery in the cytoplasm of the cell to make proteins.1 Over the past decade, research and technological innovations progressed rapidly in the field of vaccine development enabling mRNA as a promising therapeutic tool. There has been research on mRNA vaccines for infectious agents, such as…

by Anu Desai, PhD Messenger RNA (mRNA) is a single-stranded molecule of genetic code found in all living cells. As a chemical intermediary, mRNA carries instructions from deoxyribonucleic acid (DNA) in our chromosomes…

Musculoskeletal

by Michael Stanclift, ND Many of us have been using omega-3 fats, such as fish oil, for managing inflammatory conditions. Interestingly, fish oil and special molecules made from them called specialized pro-resolving mediators (SPMs) have big impacts on our immune system and play an important role in the activity of immune cells. The key lies in how fats such as the ones found in fish oil influence the behavior of the white blood cells (WBCs) of our immune system. Our…

by Michael Stanclift, ND Many of us have been using omega-3 fats, such as fish oil, for managing inflammatory conditions. Interestingly, fish oil and special molecules made from them called specialized pro-resolving mediators…

Digestive

by Anu Desai, PhD Pollution and toxic elements Environmental pollution and toxins from plastics, pesticides, smoke, contaminated water, and food have the potential to greatly impact human health.1 These toxic loads cause inflammatory and autoimmune responses, including neurodegenerative conditions including Alzheimer’s disease (AD), Parkinson’s disease (PD), and multiple sclerosis (MS).2-4 More recently, some efforts have been made to minimize the exposures to pollutants in the long run, such as: using BPA-free plastics, attempting to reduce greenhouse gasses, and incorporating clean-energy…

by Anu Desai, PhD Pollution and toxic elements Environmental pollution and toxins from plastics, pesticides, smoke, contaminated water, and food have the potential to greatly impact human health.1 These toxic loads cause inflammatory…

Digestive

by Noelle Patno, PhD What is lactoferrin? Lactoferrin is an iron-binding glycoprotein found in most body fluids (including saliva, tears, bile, small intestine secretions, vaginal secretions, and more) and highly similar across species. First identified in bovine milk in 1939, it was later isolated from human milk in 1960 and other fluids as well as blood plasma (specifically, the immune cells called neutrophils). The highest concentration may be found in human colostrum at 8 mg/mL with breast milk levels at…

by Noelle Patno, PhD What is lactoferrin? Lactoferrin is an iron-binding glycoprotein found in most body fluids (including saliva, tears, bile, small intestine secretions, vaginal secretions, and more) and highly similar across species.…

Digestive

by Noelle Patno, PhD Lactoferrin (LF) has been advocated by researchers1–3 as a potential method to prevent or treat COVID-19. These recent reviews promote a hypothesis that the natural, endogenous compound which has shown antiviral capabilities for other viruses including SARS-CoV may be effective against the SARS-CoV-2 virus as well. With over 70 years since the discovery of this glycoprotein, this iron-scavenging milk protein now deserves greater attention. The current literature demonstrates that LF has many anti-inflammatory, immunomodulatory, and even…

by Noelle Patno, PhD Lactoferrin (LF) has been advocated by researchers1–3 as a potential method to prevent or treat COVID-19. These recent reviews promote a hypothesis that the natural, endogenous compound which has…

Cognitive

by Milene Brownlow, PhD Nutritional psychiatry is a rapidly growing medical field studying the connection between the role food and diet quality plays in  how we feel.1 We intuitively understand the body-mind connection and how it affects our day-to-day. We get butterflies in our stomach when nervous, our heart races when we are excited, and our mindset quickly goes south when we have digestive problems. This connection has led researchers to investigate lifestyle modifications that may optimize mental and cognitive…

by Milene Brownlow, PhD Nutritional psychiatry is a rapidly growing medical field studying the connection between the role food and diet quality plays in  how we feel.1 We intuitively understand the body-mind connection…

Cognitive, Foundational

by Molly Knudsen, MS, RDN From a culinary perspective, mushrooms are a very polarizing food. You either love or despise them, and you either order a meal based on their inclusion or veer far away from it. There are rarely feelings of indifference. However, the notion that medicinal mushrooms are beneficial for health isn’t as divisive as their presence on the dinnerplate. Typically taken in as an extract, fungal varieties considered to be a medicinal mushroom have been used in…

by Molly Knudsen, MS, RDN From a culinary perspective, mushrooms are a very polarizing food. You either love or despise them, and you either order a meal based on their inclusion or veer…

Foundational

by Michael Stanclift, ND Introduction Many clinicians who know andrographis (Andrographis paniculata) know its anticancer properties; however, its antimicrobial mechanisms have recently caught researchers’ eyes.1-3 Andrographis has been used for its medicinal benefits in traditional Chinese medicine and Ayurveda for centuries, mostly for effects related to infections and/or the immune system.1,3 Based on computer models, some researchers hypothesize andrographolide, a major bioactive compound of andrographis, might have a role in the current COVID-19 pandemic.2,3 Andrographis demonstrates antiviral activity against a…

by Michael Stanclift, ND Introduction Many clinicians who know andrographis (Andrographis paniculata) know its anticancer properties; however, its antimicrobial mechanisms have recently caught researchers’ eyes.1-3 Andrographis has been used for its medicinal benefits…

Cardiometabolic, Foundational

by Lewis Chang, PhD Introduction “Damned if I don’t get more tired every day. Tired of what I do. Following arcs, like lobbed rocks. The inevitability of truth. But the complexity and the grey lie not in the truth, but what you do with the truth once you have it.”—Detective Benoit Blanc (played by Daniel Craig, in the 2019 film Knives Out) The current pandemic is not showing any sign of slowing in the US and many parts of the…

by Lewis Chang, PhD Introduction “Damned if I don’t get more tired every day. Tired of what I do. Following arcs, like lobbed rocks. The inevitability of truth. But the complexity and the…

Digestive

by Noelle Patno, PhD Introduction Recent findings show that not only respiratory disease but also hypertension and diabetes are prevalent comorbidities associated with COVID-19 infection.1 In fact, multiple meta-analyses indicate that individuals with high blood pressure, diabetes, or cardiovascular diseases have a higher risk for the COVID-19 disease.2–4 Metabolic disease and the immune response to infections are closely tied together in the gut, from which digestion and defense originate, as the oral route into the intestine is one major way…

by Noelle Patno, PhD Introduction Recent findings show that not only respiratory disease but also hypertension and diabetes are prevalent comorbidities associated with COVID-19 infection.1 In fact, multiple meta-analyses indicate that individuals with…

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