In the 4th part of the SPM interview series with Charles Serhan, PhD, DSc, he answers the question: “Besides peripheral blood, can pro-resolving mediators be measured in other tissues? If so, which ones?” Dr. Serhan shares current research findings on SPM measurement in the human body, demonstrating several human tissues and fluids where SPMs have been found. These discoveries will directly inform analytical methods for SPM measurement moving forward. Dr. Serhan also discusses the “coagulation clock”, as well as gender- and age-dependent differences in SPM levels.
Charles Serhan, PhD, DSc is Director of the Center for Experimental Therapeutics and Reperfusion Injury at Brigham and Women’s Hospital and Professor of Anesthesia at Harvard Medical School.