Sulforaphane found in cruciferous vegetables such as broccoli, Brussels  sprouts, cauliflower, and cabbage has been associated with the up-regulation of antioxidant and detoxification enzymes in the body. Recent studies revealed an anti-inflammatory response in patients supplementing with sulforaphane. Clinical studies showed increased detoxification of carcinogens, an indirect increase of anti-oxidative cellular potential, and inhibition of inflammation. For more information download the PDF at the link below: Download the slide deck

In 2015, Xu Wang, PhD and colleagues conducted the first comprehensive systematic review and meta-analysis of risk and protective factors for Alzheimer’s Disease that could be modified via personal, clinical and public strategy. Their findings suggested an effective diet, relevant medications, appropriate biochemical exposures, psychological condition, preexisting disease and life-style changes may be promising options for preventative strategies in Alzheimer’s Disease. Healthy dietary pattern, high folate intake, cognitive activity, high Ab42/Ab40 ratio, fish consumption, high education, physical activity and high…

While inflammation is at the root of all sorts of poor outcomes and diseases it isn’t the fault of inflammation itself. Indeed, inflammation is a natural and protective response to specific insults and injuries. Healthy inflammation resolves naturally when you get a cut, for example. When inflammation becomes chronic, however, it can become destructive to the body’s tissues and systems. Long-term, chronic inflammation due to disease, a pro-inflammatory diet, or aging should be resolved as much as possible. Download the…

This review of the evidence that the failure of resolution programs contributes to metabolic diseases and that SPMs may play pivotal roles in their resolution found that supplementing the diet with SPMs can, indeed, reduce the chronic low-grade inflammation that can be harmful. Patients with a variety of inflammatory conditions can benefit from SPMs and improved inflammation resolution. Acute inflammation is healthy for the body, but when inflammation becomes chronic, is can damage tissues and be detrimental to health. The…

Inflammaging is a term that describes how immune system function deteriorates as we age. In individuals, it is determined by a variety of interrelated genetic and environmental factors, also known as epigenetics. This infographic shows how our bodies can become susceptible to inflammating and its effects. When we are young, we typically have good resolution of inflammation, low pro-inflammatory status, and a highly efficient stress response. Thus, most healthy young people do not suffer the negative consequences of inflammaging. However,…

Acute inflammation is essential to health—and, so too, is its resolution. Pathologists divide acute inflammation into 2 parts: Initiation Resolution When microbes invade the body by barrier break, tissue injury or trauma, they set into motion a cascade of events. The first part of this cascade is the initiation phase, also known as the acute inflammatory response, and as Dr. Serhan notes, “is actually protective of the host organism” because it signals the need for the second part or resolution phase of the…

This research review on Specialized Pro-resolving Mediators (SPMs) covers a novel nutritional approach to resolve inflammation. Acute and chronic inflammation is a widespread common experience in many who suffer from weight gain, as well as cardio metabolic disease and can be brought into resolution with the introduction clinical nutrition therapy and the use of SPMs to aid in the return to homeostasis, therefore reducing inflammation. This study demonstrates the use of SPM therapy in animal models of human disease. Acute…

Introducing a Novel Nutritional Therapy & Pathway for Addressing Resolution of Inflammation 1. Novel Solution and Pathway to Support Inflammatory Responses New Clinical Benefits to Resolve Inflammation Fills a Gap in Managing Inflammatory Responses 2. Independent yet Complementary Solutions to Managing Inflammatory Conditions Not Blocking, inhibiting or suppressing inflammation Resolves’ inflammation to avoid prolongation to chronic health conditions 3. Proprietary Nutritional Solutions Specialized Pro-resolving Mediators Standardized Level of Activity 4. Clinical Uses with Superior Improvement in Ability to Resolve Inflammation Activates effective resolution response…

How does chronic inflammation reinforce and cause chronic disease? Inputs like a sedentary lifestyle, obesity, and aging are associated with chronic systems inflammation throughout the whole body. This infographic illustrates the cascade from the input to the system inflammation to the resultant disease state. Disease states associated with inflammation include type 2 diabetes, atherosclerosis, neurological diseases like Alzheimer’s disease, cancer, and arthritis. Download the infographic Handschin C, Spiegelman BM. The role of exercise and PGC1alpha in inflammation and chronic disease.…