by Lewis Chang, PhD Body mass index (BMI) is positively associated with cardiometabolic risk and insulin resistance in children according to a recent population-based study, but cardiorespiratory fitness may mitigate risk.1 Swedish researchers from the Department of Biosciences and Nutrition at Karolinska Institutet (Huddinge, Sweden) and colleagues from Spain and Chile conducted a pooled study including cross-sectional data from three projects (n=1247, aged 8-11 years old) to evaluate the impact of BMI on cardiometabolic risk and homeostatic model assessment of insulin…
by Lewis Chang, PhD Body mass index (BMI) is positively associated with cardiometabolic risk and insulin resistance in children according to a recent population-based study, but cardiorespiratory fitness may mitigate risk.1 Swedish researchers from…
by Bianca Garilli, ND Obesity has both genetic and environmental underpinnings. Research has elucidated key fat-regulating genes, one of which is the fat-mass and obesity-associated (FTO) gene located on chromosome 16q12.2. Single nucleotide polymorphisms (SNPs) on the FTO gene have been associated with an increased risk for obesity.1 Certain obesity-related SNPs have been shown to be specific to a person’s ethnic and racial makeup. As body mass index (BMI) continues to increase at an alarming rate across the globe, it is…
by Bianca Garilli, ND Obesity has both genetic and environmental underpinnings. Research has elucidated key fat-regulating genes, one of which is the fat-mass and obesity-associated (FTO) gene located on chromosome 16q12.2. Single nucleotide…
Dr. Charles Serhan of Harvard Medical School discusses what excites him most about his research in inflammation resolution and specialized pro-resolving mediators, SPMs. He reveals that the opportunity for resolution of inflammation to leave the lab and enter clinical application is most exciting to him. Research and science about stimulating resolution of inflammation are now emerging for general practice. This is a concept that has been in development for many years and it is now ready for “prime time.” SPMs…
Dr. Charles Serhan of Harvard Medical School discusses what excites him most about his research in inflammation resolution and specialized pro-resolving mediators, SPMs. He reveals that the opportunity for resolution of inflammation to…
For the past 40 years, clinical research in inflammation has been focused on blocking, suppressing or inhibiting an inflammatory response. This focus was largely driven by an interest to facilitate recovery, modulate a better immune response and to minimize or manage pain responses. And, while these approaches have resulted in symptomatic relief, unknowingly, blocking the inflammatory response resulted in suppression of an active process now known to fully resolve the inflammatory response. The outcome of this has since been shown…
For the past 40 years, clinical research in inflammation has been focused on blocking, suppressing or inhibiting an inflammatory response. This focus was largely driven by an interest to facilitate recovery, modulate a…
by Milene Brownlow, PhD It seems like we’re always on our way to a destination. Whether it’s a physical journey, such as traveling out of town, or a mental one, like getting ready for a job interview, we must prepare for the journey in order to get there. Entering a state of ketosis is no different. Strategic planning is important. What is “ketosis,” and how can you get there? Many people associate ketosis with a popular diet program and as…
by Milene Brownlow, PhD It seems like we’re always on our way to a destination. Whether it’s a physical journey, such as traveling out of town, or a mental one, like getting ready…
In Part 1 of this 2-part series, Jeff Volek, PhD, RD reviews the concept of ketogenesis, nutritional ketosis, and keto-adaptation. He discusses the utility of ketogenic diets in clinical practice and the potential benefits of the ketogenic approach to enhance physical performance, manage inflammation, and improve lifespan. Dr. Volek is a Professor in the Department of Human Sciences at The Ohio State University. For 20+ years, Dr. Volek has studied the effects of how diets extremely low in carbohydrates can induce…
In Part 1 of this 2-part series, Jeff Volek, PhD, RD reviews the concept of ketogenesis, nutritional ketosis, and keto-adaptation. He discusses the utility of ketogenic diets in clinical practice and the potential…
Ryan Lazarus, DC, MS, CNS, IFMCP If you had three wishes to improve your health, what would they be? Dr. Lazarus identifies the three main areas most patients desire improvement in: gain energy, lose weight, and improve the aging process. Dr. Lazarus discusses a therapeutic metabolic reboot via nutritional ketosis, when the body uses fat as alternative fuel by reducing overall calorie input, reducing carbohydrate intake, and maintaining adequate protein intake. He provides simple implementation strategies to help patients safely achieve ketosis…
Ryan Lazarus, DC, MS, CNS, IFMCP If you had three wishes to improve your health, what would they be? Dr. Lazarus identifies the three main areas most patients desire improvement in: gain energy, lose…
Abnormally high blood sugar in individuals with type 2 Diabetes (T2D) is associated with impaired cognitive performance, a Dutch epidemiological study finds.1 Hyperglycemia is known to cause various long-term complications such as damage to retina, nerve and kidney, cardiovascular disease, and infections. Dutch researchers from the Department of Internal Medicine at Maastricht University Medical Centre and Department of Neurology at University Medical Centre Utrecht were interested in whether differences in glucose metabolism status were associated with cognitive performance, in patients of…
Abnormally high blood sugar in individuals with type 2 Diabetes (T2D) is associated with impaired cognitive performance, a Dutch epidemiological study finds.1 Hyperglycemia is known to cause various long-term complications such as damage to…
It is estimated that by 2050, 1 in 3 U.S. individuals will have type 2 diabetes(T2D) and cardiovascular disease (CVD) is the most common cause of death for in these patients. Prevention of CVD among individuals with T2D is therefore of great public health importance. The scientific statements from the American Diabetes Association (ADA), American Heart Association (AHA) and American College of Cardiology (ACC) regarding CVD prevention for patients with T2D, and risk factors for CVD, were recently synthesized and published in…
It is estimated that by 2050, 1 in 3 U.S. individuals will have type 2 diabetes(T2D) and cardiovascular disease (CVD) is the most common cause of death for in these patients. Prevention of…
A retrospective cohort study found that infertility in women was associated with an increased risk of death from certain endocrine related disease such as diabetes and breast cancer [1]. As infertility in women may be a sign of endocrine or inflammatory disruption, scientists have had concerns about its long-term effects on women’s health. Researchers from the Reproductive Endocrinology & Infertility at the University of Pennsylvania (Philadelphia, PA) set out to study the link between infertility and mortality in women in the PLCO…
A retrospective cohort study found that infertility in women was associated with an increased risk of death from certain endocrine related disease such as diabetes and breast cancer [1]. As infertility in women may be…
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