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Articles, Cognitive, Foundational, Functional Medicine, Integrative, Naturopathic, Nutritionists

by Bianca Garilli, ND Recent research continues to support the idea that both a genetic and environmental component may be potentially associated with the development of autism spectrum disorder (ASD). Heritability is high in ASD as can be seen from family and twin studies. It is most certainly polygenic (multiple genes may contribute to ASD risk rather than there being just “one ASD gene”), and may be associated with both conserved mutations (inherited from parents) but also de novo mutations.1 The genetic risks related to ASD are highly complex…

by Bianca Garilli, ND Recent research continues to support the idea that both a genetic and environmental component may be potentially associated with the development of autism spectrum disorder (ASD). Heritability is high in ASD as can…

Articles, Cognitive, Functional Medicine, Integrative, Naturopathic, Nutritionists

Apolipoprotein E (APOE) is a type of apolipoprotein involved in various biological processes, including lipoprotein transport, immunoregulation, and even cognition. The gene that encodes APOE is called APOE gene and is polymorphic, with three major alleles (ε2, ε3 and ε4) producing 6 common genotypes (ε2/ε2, ε2/ε3, ε2/ε4, ε3/ε3, ε3/ε4, and ε4/ε4). The ε3 allele is the most common allele, and the ε3/ε3 the most common genotype in humans. The ε4 allele is a genetic risk factor for Alzheimer’s disease (AD), and for…

Apolipoprotein E (APOE) is a type of apolipoprotein involved in various biological processes, including lipoprotein transport, immunoregulation, and even cognition. The gene that encodes APOE is called APOE gene and is polymorphic, with three major…

Blogs, Cognitive, Foundational, Functional Medicine, Integrative, Naturopathic, Nutritionists

by Bianca Garilli, ND A Presidential Advisory on brain health was recently released by the American Heart Association/American Stroke Association in September 2017. The goals of the publication were to provide a definition of “optimal brain health” in adults, and guidance on how to maintain brain health through the years. From these data, the following 7 metrics were brought forward as steps to implement for improving brain health where ideal brain health was defined as “having an optimal capacity to…

by Bianca Garilli, ND A Presidential Advisory on brain health was recently released by the American Heart Association/American Stroke Association in September 2017. The goals of the publication were to provide a definition…

Articles, Cognitive, Functional Medicine, Integrative, Naturopathic, Nutritionists

by Lewis Chang, PhD  A randomized trial demonstrated that Ginkgo biloba extract (GBE) supplementation in combination with aspirin improved cognitive function after an ischemic stroke better than aspirin alone.1 Researchers from Nanjing University Medical School (Nanjing, China) conducted a randomized, open-label, single-blind trial.1 They enrolled 348 patients with an onset of acute ischemic stroke within 7 days from five hospitals in Jiangsu Province (Eastern China). Participants were randomly assigned to GBE (450 mg/day) plus aspirin (100 mg/day) or only aspirin…

by Lewis Chang, PhD  A randomized trial demonstrated that Ginkgo biloba extract (GBE) supplementation in combination with aspirin improved cognitive function after an ischemic stroke better than aspirin alone.1 Researchers from Nanjing University…

Articles, Cognitive, Functional Medicine, Integrative, Naturopathic, Nutritionists

by Ashley Jordan Ferira, PhD, RDN Three months of nutritional ketosis provided relief from chronic cluster headache (CCH), according to a study by Di Lorenzo and colleagues.1 Headache complaints are among the most commonly reported neurological disorders. Migraines affect 1 in 7 adults annually and are 2x more common in women than men. In contrast, cluster headache (CH) is rare, affecting < 1% of the population and is 6x more common in men.2 CH is the most severe type of…

by Ashley Jordan Ferira, PhD, RDN Three months of nutritional ketosis provided relief from chronic cluster headache (CCH), according to a study by Di Lorenzo and colleagues.1 Headache complaints are among the most…

Blogs, Cognitive, Foundational, Functional Medicine, Integrative, Naturopathic, Nutritionists

by Nilima Desai, MPH, RD In today’s fast-paced world it seems like most people are under some type of stress. In fact, the World Health Organization’s Global Burden of Disease Survey reports by the year 2020, stress-related conditions will be the second leading cause of disability.1 Stress is defined as, “a physical, chemical, or emotional factor that causes bodily or mental tension and may be a factor in disease causation”.2 It’s important to remember that not all stress is bad,…

by Nilima Desai, MPH, RD In today’s fast-paced world it seems like most people are under some type of stress. In fact, the World Health Organization’s Global Burden of Disease Survey reports by…

Chiropractic, Cognitive, Functional Medicine, Integrative, Naturopathic

by Ashley Jordan Ferira, PhD, RDN As part of its Breakthrough Devices Program, the FDA authorized marketing for the Brain Trauma Indicator, the first blood test to evaluate mild traumatic brain injury (TBI) in adults.1 What is TBI? TBI, also known as “concussion,” occurs following a bump, blow or jolt to the head or penetrating head injury that disrupts the brain’s normal functioning. TBI can cause short- and long-term impairments in thinking, memory, movement, sensation (e.g. vision or hearing) and…

by Ashley Jordan Ferira, PhD, RDN As part of its Breakthrough Devices Program, the FDA authorized marketing for the Brain Trauma Indicator, the first blood test to evaluate mild traumatic brain injury (TBI)…

Articles, Cognitive, Foundational, Functional Medicine, Integrative, Nutritionists

by Lewis Chang, PhD  It has been suggested that oxidative stress contributes to the pathogenesis of Parkinson’s disease (PD), an age-related neurodegenerative disorder of the central nervous system affecting movement. As antioxidants may offset oxidative stress and damage to neurons, scientists have been interested in whether antioxidant consumption would reduce the risk of PD. Researchers from Karolinska Institutet (Stockholm, Sweden) and University of Southern California (Los Angeles, CA) set out to investigate the association between antioxidant intake and PD risk…

by Lewis Chang, PhD  It has been suggested that oxidative stress contributes to the pathogenesis of Parkinson’s disease (PD), an age-related neurodegenerative disorder of the central nervous system affecting movement. As antioxidants may…

Articles, Cardiometabolic, Cognitive, Functional Medicine, Naturopathic, Nutritionists

Abnormally high blood sugar in individuals with type 2 Diabetes (T2D) is associated with impaired cognitive performance, a Dutch epidemiological study finds.1 Hyperglycemia is known to cause various long-term complications such as damage to retina, nerve and kidney, cardiovascular disease, and infections. Dutch researchers from the Department of Internal Medicine at Maastricht University Medical Centre and Department of Neurology at University Medical Centre Utrecht were interested in whether differences in glucose metabolism status were associated with cognitive performance, in patients of…

Abnormally high blood sugar in individuals with type 2 Diabetes (T2D) is associated with impaired cognitive performance, a Dutch epidemiological study finds.1 Hyperglycemia is known to cause various long-term complications such as damage to…

Articles, Cognitive, Foundational, Functional Medicine, Integrative, Naturopathic, Nutritionists

by Bianca Garilli, ND, IFMCP Across the world autism spectrum disorder (ASD) rates vary greatly; making it difficult to confirm definitive numbers particularly in many countries that do not actively track rates or publicly report their statistics. However, data from countries such as Poland where it is reported that 3 in 10,000 children are diagnosed with ASD, or Hong Kong where ASD afflicts 327 in 10,000 children and in the US where in 2015 there were 222 in 10,000 children…

by Bianca Garilli, ND, IFMCP Across the world autism spectrum disorder (ASD) rates vary greatly; making it difficult to confirm definitive numbers particularly in many countries that do not actively track rates or…

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