by Bianca Garilli, ND Globally, 39% of adults aged ≥18 years were classified as overweight and 13% obese in 2016, totaling a jaw-dropping 1.9 billion adults overall.1 With obesity rates soaring, tripling worldwide since 1975, most of the Earth’s population now lives in countries where overweight and obesity cause more morbidity and mortality than being underweight.1 Keeping pace with these gains in adiposity is the behemoth weight loss and weight management market, which consists of fitness centers, slimming centers, consulting…

by Bianca Garilli, ND Telomeres are the DNA-protein caps found at both ends of eukaryotic chromosomes. They serve to protect the chromosome from degradation, unnecessary recombination, deleterious repairs at the chromosome ends, and interchromosomal fusion.1-3 In summary, they function to preserve the stability of the genome.1-3 The length of the cell’s telomeres shorten with every cell division and, upon reaching a critical length, trigger the cell to either undergo the process of apoptosis (programmed cell death) or senescence (cells stop…

by Bianca Garilli, ND Coronary heart disease (CHD) is the most common form of heart disease in the US, resulting in over 370,000 deaths annually.1 Because of its frequent and often fatal nature, it is important to understand the risk factors associated with heart disease and ways to mitigate that risk. A partial list of common CHD risk factors include: elevated blood pressure and cholesterol levels, diabetes and prediabetes, smoking, overweight or obesity, sedentary lifestyle, family history of early heart…

by Noelle Patno, PhD Research has demonstrated that probiotics not only help with gastrointestinal (GI) health but they also support immune health. Specifically, meta-analyses have shown that probiotics help reduce the incidence and duration of colds (AKA acute upper respiratory tract infections [URTI]).1-2 The length of the cold may be reduced by almost a day, resulting in less absenteeism from work, school, or day care.3 This can be significant considering that adults experience ~2-4 URTI episodes per year, with an estimated…

by Melissa Blake, BSc, ND By 2020, more than 20% of the US population will be 65 and over.1 Healthy aging is and will continue to be an important focus in many Functional Medicine offices. Sarcopenia, the gradual loss of muscle mass that occurs in healthy adults as they age, begins after the age of 30 and accelerates after 60. The difference between the muscle mass of a 20-year-old vs. an 80-year-old is about 30%.2 Loss of muscle contributes to…

by Noelle Patno, PhD Colonoscopy is one of the most common medical procedures, used for screening various bowel diseases, including colon cancer, to examine for any pathological findings (e.g. polyps, ulcers, or inflamed tissue). Barriers to colonoscopy include patients’ fears related to invasiveness, pain, or complications.1 Complications may be as minor as bloating or as severe as bowel perforation (rare); factors that may predict increased risk for complication include insufficient bowel preparation (not completely cleaned out and therefore more difficult…

by Bianca Garilli, ND It’s a well-known fact that cruciferous vegetables, including broccoli, Brussels sprouts, cauliflower, cabbage, and many others, should be a major cornerstone of any healthy, nutrient-dense diet. Not as well known, however, is that the bioavailability of some of the most desired nutritional bioactives from the Brassica vegetables, including isothiocyanates (e.g. sulforaphane), will vary depending on numerous factors. These factors can be broken down into plant-intrinsic and plant-extrinsic components. Plant-Intrinsic Factors Mainly found in cruciferous vegetables, glucosinolates (GL)…

by Bianca Garilli, ND Obesity, a preventable condition, has tripled worldwide since 1975, with 340 million children and adolescents between 5-19 years of age with overweight or obesity in 2016 according to the World Health Organization (WHO).1 In children and adolescents, BMI-for-age growth charts are used to determine weight status; >85th and <95th percentile is considered overweight, while ≥95th percentile is obese.2 In the US, overweight and obesity disproportionally affect children of low-income households, whereas the risk of overweight and…

by Bianca Garilli, ND   Polyphenol Overview Polyphenols are naturally occurring secondary metabolites found in plants. In nature they protect against ultraviolet radiation and play a role in defending against pathogens. Over 8,000 polyphenolic compounds have been identified from a large variety of plant species.1 Based on the structure and number of phenol rings they contain, polyphenols are classified into 4 main groups: phenolic acids, flavonoids, stilbenes, and lignans.1 Phenolic Acids Phenolic acids are found extensively throughout the plant kingdom,…

by Ashley Jordan Ferira, PhD, RDN   Heart disease is killer Cardiovascular disease is the #1 cause of mortality globally (17.9 million deaths annually),1 so it makes sense that researchers, clinicians, and health policymakers want to hunt down the culprit(s) of the heart disease epidemic. Recognized risk factors for heart disease include overweight and obesity, hypertension, dyslipidemia, excessive alcohol consumption, physical inactivity, and smoking.2 With the exception of smoking and physical activity habits, one’s nutrition choices (i.e., diet) can mitigate…