Clinicians and healthcare practitioners have a unique opportunity in advocating lifestyle medicine because patients see them as a reliable source of advice. However, there are still numerous technical and logistic challenges to overcome before personal “big data” can be translated into actionable and clinically relevant solutions. Clinicians are also facing various issues prior to bringing personalized lifestyle medicine to their practice. Nevertheless, emerging ground-breaking research projects have given us a glimpse of how systems thinking and computational methods may lead…

During periods of over-nutrition, excess energy is stored in white adipose tissue (WAT); continuing expansion of WAT may lead to obesity. Obesity alters the cellular physiology of adipocytes, the cells of WAT. In the context of obesity, adipocytes secrete elevated levels of free fatty acids and adipokines, but decreased levels of adiponectin. These pathophysiologic changes have many effects. Elevated free fatty acids contribute to insulin resistance, oxidative stress, inflammation, and impaired arterial flow regulation Download the PDF

The clinical results of a randomized controlled research study that showed a diabetes-specific nutrition formula for glucose control in combination with a structured dietary plan resulted in significant reduction in HbA1c levels and body weight in overweight and obese patients with type 2 diabetes (T2D) compared to an individualized dietary plan alone. The study, conducted by the Joslin Diabetes Center, was presented at the American Diabetes Association’s 76th Scientific Sessions in New Orleans, Louisiana. "Effective management of A1c levels, while challenging, is…

This research review discusses how the combination of undenatured type II collagen and tetrahydro iso-alpha acids help revitalize joint function and support an active lifestyle. Arthritis is not a single condition. In fact, there are more than 100 different forms of arthritis. The 2 most common types of arthritis, whose main feature is joint pain, are osteoarthritis (OA) and rheumatoid arthritis (RA). OA is a degenerative joint disease characterized by active bone remodeling, articular cartilage degradation, and synovial inflammation resulting…

This paper is entitled, “Supplementation with Specialized Pro-Resolving Mediators Reduces Inflammatory Biomarkers and Improves Reported Clinical Symptomology in Subjects with Chronic Inflammatory Conditions: Results from a Multi-Center Open-Case Series” Highlights: Inflammation has 2 phases: initiation and resolution. Many chronic health issues are linked to unresolved inflammation Specialized pro-resolving mediators (SPMs) are endogenous molecules essential for resolution of inflammation but may not be produced in required levels in certain condition Multi-center case study assessed effects of a proprietary SPM supplement (LM-O3)…

A review published in Alimentary Pharmacology and Therapeutics showed alcohol consumption adversely altered gut microbiota and could lead to negative impacts on the liver. It is well known that alcohol intake directly and adversely affects the liver, but more recently, it has also been clinically shown to impact the gastrointestinal microbiota. To better elucidate this relationship the authors utilized the PubMed data base, to identify and review data from research articles addressing this topic. The studies that the authors identified showed alcohol…

by Bianca Garilli, ND An article published in the New England Journal of Medicine  reviewed data collected from 1998-2012 from adults in the Swedish National Diabetes Register with type 1 diabetes (T1D) and type 2 diabetes (T2D).  Information was analyzed for various end points including overall mortality rate and incidence of cardiovascular disease (CVD) and coronary heart disease (CHD). Results from the study showed that during the observed time period the incidence rates of CVD and overall mortality rates decreased in both…

This video series is from conversations with Charles Serhan, PhD, DSc, during the recent 15th International Conference on Bioactive Lipids in Cancer, Inflammation and Related Diseases held Oct. 22-24, 2017 in Puerto Vallarta, Mexico. In this quick video, Dr. Serhan discusses ongoing research centers that are conducting research to assess SPMs efficacy in a variety of health conditions, as well as revealing additional human tissues where SPMs have been found. Charles Serhan, PhD, DSc is Director of the Center for…

by Bianca Garilli, ND The World Health Organization (WHO) estimates the total number of people living with diabetes in 2014 was 422 million, equal to approximately 8.5% of adults worldwide– a majority of whom were diagnosed with type 2 diabetes (T2D). These figures are a staggering increase from the estimated 108 million people, globally, who were diagnosed with diabetes in 1980!1 The United States does not fare any better.  According to the Centers for Disease Control and Prevention, 29.1 million people…

Patients with diabetes often have numerous comorbid conditions such as obesity, heart disease, kidney disease and hypertension to name a few. Hypertension or high blood pressure (BP), in particular, can lead to increased risks for atherosclerotic cardiovascular disease (ASCVD), heart failure (HF) and attendant microvascular complications. The last time the American Diabetes Association (ADA) provided a position statement on hypertension was more than 15 years ago. Given the increasing rise in the numbers of people afflicted by diabetes, increased BMI…