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The phytochemical xanthohumol is a flavonoid found in the flowers of hops (Humulus lupulus L.), a plant that has long been used in medicine for various applications and also in brewing of beer. The Xanthohumol Research Review explores the sources, bioavailability, and known biological properties and effects of xanthohumol, with a focus on its anti-inflammatory and antioxidant properties via kinase modulation, which have implications for metabolic pathways related to chronic conditions. View the Research Review to learn more

The phytochemical xanthohumol is a flavonoid found in the flowers of hops (Humulus lupulus L.), a plant that has long been used in medicine for various applications and also in brewing of beer.…

Probiotics from the Lactobacilli and Bifidobacteria genera are some of the most commonly studied and used. Two specific probiotic strains, Lactobacillus rhamnosus GG (LGG®)* and Bifidobacterium animalis subsp. lactis BB-12 (BB-12®)*, have been extensively researched for safety and efficacy, particularly in the pediatric population. The LGG® and BB-12® Research Review examines the clinical evidence for these two probiotic strains as a primary preventive and management strategy for many of the most common infectious diseases and skin disorders affecting children. View…

Probiotics from the Lactobacilli and Bifidobacteria genera are some of the most commonly studied and used. Two specific probiotic strains, Lactobacillus rhamnosus GG (LGG®)* and Bifidobacterium animalis subsp. lactis BB-12 (BB-12®)*, have been…

Inflammation is an immune response to insults like injuries, infections, or unhealthy dietary patterns. It is critical to control and resolve inflammation to prevent chronic inflammatory conditions. Specialized pro-resolving mediators (SPMs) are produced from long-chain polyunsaturated fats, especially EPA and DHA. The SPM Research Review examines the benefits of resolution-based nutrition and how SPMs, unique lipid mediators, play an indispensable role in switching an inflammatory response in the direction of resolution and homeostasis. View the Research Review to learn more

Inflammation is an immune response to insults like injuries, infections, or unhealthy dietary patterns. It is critical to control and resolve inflammation to prevent chronic inflammatory conditions. Specialized pro-resolving mediators (SPMs) are produced…

Oral digestive enzymes are a useful adjunctive therapy for individuals avoiding dietary gluten as a result of gluten sensitivity, intolerance or celiac disease. Aspergillus niger prolyl endoprotease (AN-PEP) is an extensively studied, gluten-digesting enzyme that is naturally occurring from the A. niger microorganism. It is resistant to the pH extremes and endogenous digestive enzymes found in the gastrointestinal tract. The AN-PEP Research Review examines the purpose, origin, actions (i.e., breaking down gluten peptides and intact gluten proteins), and clinical study…

Oral digestive enzymes are a useful adjunctive therapy for individuals avoiding dietary gluten as a result of gluten sensitivity, intolerance or celiac disease. Aspergillus niger prolyl endoprotease (AN-PEP) is an extensively studied, gluten-digesting…

Consumption of fruits, vegetables, herbs, and spices is associated with reduced risk of many chronic diseases. Only in the past few decades has research revealed that plants produce a wide variety of phytochemicals, commonly referred to as phytonutrients, which play unique roles in human health. The Phytonutrients Research Review explores plant-based dietary patterns, with a focus on the Mediterranean diet, followed by a detailed discussion of the health benefits of various phytonutrients and their associated biological mechanisms. View the Research…

Consumption of fruits, vegetables, herbs, and spices is associated with reduced risk of many chronic diseases. Only in the past few decades has research revealed that plants produce a wide variety of phytochemicals,…

Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are long-chain polyunsaturated omega-3 fatty acids derived from marine sources, such as oily fish and fish oil or algal products. EPA and DHA act in the body via cell membrane incorporation, specific cellular receptors, and the generation of critical down-stream lipid mediators such as eicosanoids and specialized pro-resolving mediators (SPMs). The EPA & DHA Research Review covers the sources, recommendations, functions, and various areas of clinical support for EPA and DHA, including cardiovascular,…

Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are long-chain polyunsaturated omega-3 fatty acids derived from marine sources, such as oily fish and fish oil or algal products. EPA and DHA act in the…

Positive associations have been found between rising obesity/body mass index (BMI) levels and Clostridium difficile infections (CDI) rates. Additionally, recent studies point to changes in the human microbiome as a potential mechanism for increased rates of CDI, along with the obvious increase in CDI prevalence associated with the use of proton pump inhibitors (PPIs) for gastroesophageal reflux disease (GERD), a common occurrence in those with elevated BMI. Download the Clinical Review to learn more

Positive associations have been found between rising obesity/body mass index (BMI) levels and Clostridium difficile infections (CDI) rates. Additionally, recent studies point to changes in the human microbiome as a potential mechanism for increased rates of…

This presentation provides a brief overview on the historical use and known medicinal actions of turmeric root, ginger root, hops flowers and Indian frankincense. It describes key active constituents including curcuminoids, gingerols, xanthohumol, and boswellic acids. Several figures delve into the biologic mechanisms of action of these constituents as they relate to local and systemic inflammation and pain. Mechanisms discussed include the upstream and downstream modulation of enzymes, prostaglandins, gene expression regulators, pro-inflammatory cytokines, and chemokines. Also described is clinical…

This presentation provides a brief overview on the historical use and known medicinal actions of turmeric root, ginger root, hops flowers and Indian frankincense. It describes key active constituents including curcuminoids, gingerols, xanthohumol,…

Maintaining a healthy weight is not easy, but it is possible. This clinical review covers various factors influencing successful long-term weight loss maintenance. The World Health Organization’s statistics indicate that most of the world’s population now lives in a country in which overweight and obesity contribute to more mortality than underweight. This trend has led to a worldwide obesity rate that has tripled since 1975. If this rate of overweight incidence continues, nearly half of the world’s adult population will be…

Maintaining a healthy weight is not easy, but it is possible. This clinical review covers various factors influencing successful long-term weight loss maintenance. The World Health Organization’s statistics indicate that most of the world’s…

Did you know?... Over 12% of the US population will develop a thyroid condition during their lifetime Up to 60% of individuals with thyroid disease are unaware of their condition Hypothyroidism is the 2nd most common endocrine disorder affecting women of reproductive age Thyroid hormone (TH) is essential for life and has numerous, critical functions in the body. In addition to regulating metabolism and mediating body weight and energy levels, TH is also involved in regulating many vital body functions…

Did you know?... Over 12% of the US population will develop a thyroid condition during their lifetime Up to 60% of individuals with thyroid disease are unaware of their condition Hypothyroidism is the…

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