As the current pandemic rages on, several hundred clinical trials are recruiting and ongoing hoping to identify efficacious antiviral and anti-inflammatory strategies. In a new commentary published in the journal Cancer Metastasis and Reviews (Springer Nature publishing group),1 a group of prominent researchers proposed a promising, complementary direction worthy of consideration: targeting inflammation resolution. Who contributed to this commentary? The article was led by Dipak Panigrahy, MD, at Beth Israel Deaconess Medical Center of Harvard Medical School, who has had…

The elimination diet gives specific experiential evidence about reactions to foods that can motivate people to make changes. As with most protocols, the challenge is compliance. Join us as Deanna Minich, PhD, CNS, FACN, IFMCP provides the three key principles to share with patients before starting them on an elimination diet.

by Sara Gottfried, MD and Bianca Garilli, ND, IFMCP Introduction We’re just starting to understand the full spectrum of toxic threats to the human body, including obesity. What’s clear is that the body doesn’t know what to do with our myriad exposures to toxins. They clog the liver, then get stored in fat, and ultimately back up into the brain. Since the brain is almost two-thirds fat (the fattiest organ in the body), it makes sense that it’s likely the…

Host: Deanna Minich, PhD, CNS, FACN, IFMCP Guest: Deborah Maragopoulos, MN, FNP "The hypothalamus is like the CEO of your entire body. Everything else are workers." – Deborah Maragopoulos, MN, FNP In this edifying discussion, Deborah Maragopoulos, FNP and Deanna Minich, PhD explore the neuro-immune-endocrine system and how the hypothalamus, specifically, is at the core of many patients’ chronic health issues, from mood and metabolic disorders to insomnia and autoimmunity. Over 30+ years of working in healthcare, Deborah explains that her…

Vitamin D deficiency is a global pandemic, and the clinical impact is far-reaching for pediatric and adult patients. In this video, Dr. Sara Gottfried discusses the US Endocrine Society guidelines for vitamin D sufficiency and explains the differential impact of vitamin D2 vs. D3 supplementation on serum 25-hydroxyvitamin D levels – 25(OH)D. Next, she provides insights on the synergistic role of vitamins D and K in bone and cardiovascular health. Since both of these essential, fat-soluble micronutrients are major nutrient…

Host: Deanna Minich, PhD, CNS, FACN, IFMCP Guest: Karima Hirani, MD, MPH In this cutting edge discussion, Drs. Karima Hirani and Deanna Minich discuss pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS), honing in on its clinical presentation, assessment, and treatment options in both pediatric and adult patients. PANDAS is thought to arise from the development of brain-reactive autoantibodies following infection by a group A streptococcus (GAS). PANDAS is an episodic condition typified by a sudden onset of obsessive compulsive…

by Bianca Garilli, ND, USMC Veteran Energy drinks have become a common sight in today’s fast-paced, “get the job done” world. In fact, according to the National Institutes of Health (NIH), next to multivitamins, energy drinks are currently the most popular dietary supplement consumed by American teens and young adults.1 These drinks are marketed as a means to improve energy, stamina, athletic performance, and concentration, as well as reducing fatigue.1-3 Energy drinks are sometime considered “functional beverages” while also falling…

by Sara Gottfried, MD Exercise is key to overall health, but sometimes the wrong approach can do more harm than good. It’s likely one of the reasons you’ve encountered patients who are struggling to achieve results despite every effort to lose weight and improve their health. Thankfully, there’s more to the story. We sat down with Sara Gottfried, MD to discuss the connection between exercise, hormones, and healthy weight loss. Sometimes exercising too much can make it more difficult for…

by Sara Gottfried, MD and Lewis Chang, PhD Introduction When I finished my medical training in 1998 at the University of California at San Francisco, I thought I knew everything about vitamin D, particularly vitamin D deficiency and insufficiency. I understood vitamin D was important for the efficient trafficking of calcium in the body, and that helps to keep bones strong, which was important for women’s health over the age of thirty when bone density begins to decline. What I…

by Bianca Garilli, ND, IFMCP, USMC Veteran Apolipoprotein E (ApoE) is a lipoprotein encoded by the apolipoprotein E (APOE) gene located on chromosome 19; this protein is primarily responsible for transporting and metabolizing cholesterol and other lipids.1 Although expressed in various tissues throughout the body, the highest ApoE concentrations are found in the liver, kidney, spleen, adrenal, adipose tissue, and the brain or central nervous system (CNS), where it is predominately involved in neuronal maintenance, growth, and repair.1,2 There are…