Search Results for: SPM

Inflammaging is a term that describes how immune system function deteriorates as we age. In individuals, it is determined by a variety of interrelated genetic and environmental factors, also known as epigenetics. This infographic shows how our bodies can become susceptible to inflammating and its effects. When we are young, we typically have good resolution of inflammation, low pro-inflammatory status, and a highly efficient stress response. Thus, most healthy young people do not suffer the negative consequences of inflammaging. However,…

This research review on Specialized Pro-resolving Mediators (SPMs) covers a novel nutritional approach to resolve inflammation. Acute and chronic inflammation is a widespread common experience in many who suffer from weight gain, as well as cardio metabolic disease and can be brought into resolution with the introduction clinical nutrition therapy and the use of SPMs to aid in the return to homeostasis, therefore reducing inflammation. This study demonstrates the use of SPM therapy in animal models of human disease. Acute…

How does chronic inflammation reinforce and cause chronic disease? Inputs like a sedentary lifestyle, obesity, and aging are associated with chronic systems inflammation throughout the whole body. This infographic illustrates the cascade from the input to the system inflammation to the resultant disease state. Disease states associated with inflammation include type 2 diabetes, atherosclerosis, neurological diseases like Alzheimer’s disease, cancer, and arthritis. Download the infographic Handschin C, Spiegelman BM. The role of exercise and PGC1alpha in inflammation and chronic disease.…