Host: Deanna Minich, PhD, CNS, FACN, IFMCP Guest: Deborah Maragopoulos, MN, FNP "The hypothalamus is like the CEO of your entire body. Everything else are workers." – Deborah Maragopoulos, MN, FNP In this edifying discussion, Deborah Maragopoulos, FNP and Deanna Minich, PhD explore the neuro-immune-endocrine system and how the hypothalamus, specifically, is at the core of many patients’ chronic health issues, from mood and metabolic disorders to insomnia and autoimmunity. Over 30+ years of working in healthcare, Deborah explains that her…

by Melissa Blake, BSc, ND Mental health continues to be a growing concern worldwide. Both Statistics Canada and The National Institute of Mental Health estimate that 1 in 5 Canadians and Americans live with a mental illness.1,2 The World Health Organization lists depression as the #1 cause of disability globally.3 Considering the rising rates and significant disease burden of mental illness, the increasing level of interest in novel clinical support options is no surprise. One such option being explored is…

by Lewis Chang, PhD and Annalouise O’Connor, PhD, RD High-density lipoprotein (HDL) is best known for its ability to carry cholesterol from the blood to the liver for elimination. HDL also facilitates other cardioprotective effects in the body through anti-inflammatory, anti-oxidative, and antithrombotic actions.1,2 However, for HDL to have these benefits, it needs to be functional. Loss of HDL function, or worse, gain of HDL dysfunction can negatively impact cardiometabolic health.3 In addition to cholesterol, HDL can accumulate other molecules,…

by Sara Gottfried, MD Exercise is key to overall health, but sometimes the wrong approach can do more harm than good. It’s likely one of the reasons you’ve encountered patients who are struggling to achieve results despite every effort to lose weight and improve their health. Thankfully, there’s more to the story. We sat down with Sara Gottfried, MD to discuss the connection between exercise, hormones, and healthy weight loss. Sometimes exercising too much can make it more difficult for…

by Bianca Garilli, ND Screen time is quickly becoming one of the hottest topics for parents, healthcare practitioners, and educators. How much screen time should children and adolescents be allowed per day? Does screen time include the time spent on laptops to complete homework and reading assignments for classes? At what age should children begin to use screens? When is an appropriate developmental timeframe to buy your child a phone? Does the use of screens increase the risks of behavioral…

by Bianca Garilli, ND, USMC Veteran The estimated cost of diabetes in the US was $327 billion in 2017, which reflects both direct medical costs ($237 billion) and indirect costs ($90 billion).1 After adjusting for inflation, this amounted to a 26% increase in diabetes costs from 2012 to 2017 and accounted for 1 in 4 healthcare dollars spent in the US.1 In 2015 it was estimated that 30.3 million people of all ages, roughly 9.4% of the US population, had…

by Sara Gottfried, MD My granny blinked behind her glasses as she drove us to her home after school, trying to conceal her panic. It was 1975. I was 7 years old, and she was 50. Granny wasn’t sure where to turn her Oldsmobile Cutlass Supreme next. The distance between the school bus stop and her home was only 5 miles, but we were lost. When my grandmother’s memory and then her personality drained out of her due to Alzheimer’s…

by Sara Gottfried, MD and Annalouise O’Connor, PhD, RD Many women notice after age 45 that fat seems to accumulate readily at the waist. There are even terms for it, like menopause belly, muffin top, or “menopot.” What does the science tell us about menopausal belly fat and how to get rid of it? What are the hormonal drivers and are they amenable to change with personalized lifestyle medicine? Certainly belly fat, specifically subcutaneous and visceral abdominal fat, increases during…

by Bianca Garilli, ND Type 2 diabetes (T2D) is estimated to affect nearly 15 million adult women in the US.1 This chronic disease can lead to a host of medical concerns including detrimental effects on bone health, making T2D an independent risk factor for bone fractures.2 A study published in Menopause sought to assess the status of bone mass, bone microarchitecture, and factors associated with vertebral fracture in postmenopausal women with T2D.3 This is a particularly important research query to…

by Melissa Blake, BSc, ND The use of probiotics has grown substantially over the last several years. Propelled by development in sequencing methods and analytical techniques, there has been a significant increase in knowledge and understanding about the importance of a healthy microbiome.1 The currently accepted definition of a probiotic states they are “live microorganisms which when administered in adequate amounts confer a health benefit on the host”.2 Is this relatively broad definition sufficient for clinicians to guide treatment? Can…