Gail Cresci, PhD, RD, LD, CNSc: The Gut Microbiome in Health and Disease 2-part series, "Therapeutic Manipulations of Gut Microbiota – Module 2" In this module Dr. Gail Cresci discusses the therapeutic manipulations of gut microbiota, including methods for managing peptic ulcers. Dr. Cresci explores the use of fecal microbiota transplants to manage recurrent C. difficile infection, as well as the benefits of pre- and probiotics for specific ailments. Dr. Cresci’s research examines the desirable properties of specific probiotic strains, their…

Gail Cresci, PhD, RD, LD, CNSc: The Gut Microbiome in Health and Disease 2-part series, “Diversity of the Gut Microbiota and the Host – Module 1” In this module Dr. Gail Cresci discusses the diversity of the gut microbiome and its influences on the host, as well as the associations of gut dysbiosis and synbiosis. Dr. Cresci's research has led to a greater understanding of the impact of the gut microbiota on metabolism, gene expression and immune function, as well…

In this presentation Gail Cresci, PhD, RD reviews how digestive health is enhanced when the gut microbiome is rich in diverse micro flora. This diversity is supported when preferred energy sources for the bacteria are available and support the viability of microbiota. The importance of these combinations lies in the fact that a metabolic environment is created which in turns provides protection of the gut barrier, optimal immune response and normal gut function and influences on a variety of other…

In this video, Gail Cresci, PhD, RD, LD, CNSC from the Cleveland Clinic discusses the microbiome and whether synbiotics, synergistic combination of pre- and probiotics, make a difference. She covers the rationale for synbiotic use, synbiotic approaches, supporting evidence for health outcomes. Presented at ASPEN Clinical Nutrition Week 2015. View the Slide Deck

Rob Knight, PhD is a pioneer in the study of microbiomes, in humans, animals, and the environment. He says “the three pounds of microbes that you carry around with you might be more important than every single gene you carry around in your genome.” Dr. Knight is the author of a popular TED book, Follow Your Gut: The Enormous Impact of Tiny Microbes, which explores how microbes impact your health, mood, and more. In this TED Talk, Dr. Knight discusses…

Robert Martindale, MD proposes that we have been so lost in trying to prevent inflammation that we have forgotten about the resolution of inflammation. Resolution is an active process. Anti-inflammation is not equivalent to Pro-Resolution. SPMs are lipid compounds isolated in many human tissues during inflammation. 1) Chemically synthesized in lab and in vivo 2) Injected into humans at physiologic doses 3) Inflammation resolves faster – mimics natural healing 4) Prevents transition to chronic inflammation 5) Increases bacterial and viral…

In this webinar, Dr. Osama Hamdy, the medical director of the obesity program at the Joslin Diabetes Center, discusses, “Dietary Fat: Should We Change Recommendations.” He begins with basic information on dietary fats. There are three types of lipids: free fatty acids, compound lipids (phospholipids, sterols/cholesterol). When we discuss fatty acids, we mean a chain of carbon atoms, one end called the alpha end, and one called the omega end. It is from that structure that we get the names of polyunsaturated…

Probiotics Video Animation This animation is designed for the educational use of clinicians and patients. The human gut is home to over 100 trillion bacterial cells, known as the gut microbiota. The bacteria are diverse and contain mostly “good” bacteria that help process the foods we consume and produce vitamins and short-chain fatty acids that help our bodies to function. The gut bacteria also produce metabolites that communicate with the brain and the rest of the body. They may influence…

Dr. Charles Serhan of Harvard Medical School discusses what excites him most about his research in inflammation resolution and specialized pro-resolving mediators, SPMs. He reveals that the opportunity for resolution of inflammation to leave the lab and enter clinical application is most exciting to him. Research and science about stimulating resolution of inflammation are now emerging for general practice. This is a concept that has been in development for many years and it is now ready for “prime time.” SPMs…

In Part 1 of this 2-part series, Jeff Volek, PhD, RD reviews the concept of ketogenesis, nutritional ketosis, and keto-adaptation. He discusses the utility of ketogenic diets in clinical practice and the potential benefits of the ketogenic approach to enhance physical performance, manage inflammation, and improve lifespan. Dr. Volek is a Professor in the Department of Human Sciences at The Ohio State University. For 20+ years, Dr. Volek has studied the effects of how diets extremely low in carbohydrates can induce…