by Bianca Garilli, ND In individuals with overweight or obesity, it only takes a 5% reduction in body weight to create potentially significant improvements in LDL and total cholesterol, blood pressure, and blood glucose.1 The challenge in the weight loss field however, is often less about losing this initial 5% but rather maintaining the loss over an extended period of time. In fact, only 20% of people maintain their weight loss over the long-term, with 10-80% of individuals returning to their…

This 12-week study evaluated the efficacy and safety of a nutritional product containing n-enriched tetrahydro iso-alpha acids and undenatured type 2 collagen in participants with chronic joint pain (including pain from symptomatic osteoarthritis and from rheumatoid arthritis). Tetrahydro iso-α acids (THIAAs), derived from Humulus lupulus (hops), have demonstrated anti-inflammatory effects in vitro and in an animal model of rheumatoid arthritis (RA). Undenatured type 2 collagen has been found to be effective in clinical studies in RA and osteoarthritis (OA). OBJECTIVE:…

Lactobacillus salivarius UCC118 is a well-characterized and evidence-based probiotic strain. A feeding study led by Fergus Shanahan, MD and his research group at the University College Cork was conducted in patients with ulcerative colitis. This pilot-scale, open-label study aimed to determine the ability of L. salivarius UCC118 to adhere to human enterocyte epithelial cells. The bacterial strain was administered to patients with ulcerative colitis at ~109 CFU/day for 12 days. Biopsy specimen analyses demonstrated that the ingested bacteria effectively adhered to…

In this presentation “Novel Clinical Insights on Inflammation: Resolving not Blocking,” Andrew Heyman, MD, MHSA shares clinical experiences and observations related to health conditions associated with increased inflammatory biomarkers. Dr. Heyman explores the role of specialized pro-resolving mediators (SPMs) in the clinical management of chronic inflammatory conditions, such as chronic pain and fibromyalgia, focusing on evidence from a multi-center case series investigation. Dr. Heyman concludes with insights on novel clinical targets for resolvins in neuroinflammation, in addition to providing a…

In this video, Dr. Fergus Shanahan presents “An Overview of the Human Microbiome.” Originally delivered at ASPEN in 2015, this presentation provides a glimpse of success stories in the past with microbiome, as well as a glimpse into the future of using probiotics as preventive and treatment-focused therapies. He chooses to discuss the microbiome as a therapeutic target in the body. He also discusses the use of microbial biomarkers in the body for diagnostic testing. There are very few such…

Dale E Bredesen, MD, is the director of the Easton Center for Alzheimer’s Disease Research at the University of California, Los Angeles (UCLA). He is also the principal investigator in Alzheimer’s Disease at the center. Dr. Bredesen has taken a novel approach to clinical management of cognitive decline by integrating nutrition and lifestyle medicine into practice. Based on his research and clinical practice, we may be entering the era of treatable Alzheimer’s Disease. He also discusses Mild Cognitive Impairment (MCI)…

The purported roles of the microbiota is ever emerging, and the associated technology is rapidly changing, but what do we know today? In this presentation, Mark Lyte, PhD, MS, MT (ASCP) discusses, “The Microbiota-Gut-Brain Axis: Shared Neurochemistry and Its Potential Role in Infection and Behavior.” Dr. Lyte reviews recent literature on the microbiome, taking a long-range view of the microbiome field and where it may be headed. He discusses the microbiota from a neuroendocrine vantage point. Dr. Mark Lyte is…

In this presentation Lars Bode, PhD, Associate Professor of Pediatrics at the University of California San Diego, examines how the microbiome develops in the early stages of infant feeding. He explains how human milk oligosaccharides (HMOs) differ from infant formula oligosaccharides and the unique value of HMOs shaping the gut microbiome in infants and also potentially impacting the adult gut, too. Presented at the 2015 Nutrition Pro Symposium .

by Lewis Chang, PhD A yearlong lifestyle intervention that utilized a ketogenic diet significantly improved HbA1c, body weight, and multiple cardiovascular disease (CVD) risk factors in patients with type 2 diabetes (T2D), according to data from a clinical study published in two journals.1,2 CVD is the leading cause of death among patients with T2D.3 As the prevalence of T2D continues to increase rapidly worldwide, effective interventions to address T2D and CVD risk are critical. A low-carbohydrate diet is one of…

by Bianca Garilli, ND  Traumatic brain injury (TBI) research has grown rapidly in the past decade as awareness of the high prevalence and its potential devastating consequences have become clearer.1 TBI may result in varying degrees of paralysis, loss of consciousness, amnesia and even death. Death was the most common outcome for those diagnosed with moderate and severe TBI where severity of TBI was classified according to the Glasgow Coma Scale (GCS). The two most common causes of TBI globally…