Specialized pro-resolving mediators (SPMs) offer an exciting opportunity to treat and manage the inflammation often associated with chronic disease. In this short video, Metagenics Institute asks Dr. Charles Serhan of Harvard Medical School about the significance of resolution physiology in the healthcare system today. Dr. Serhan responded that while resolution physiology has been known for decades, it has not been studied in detail of mechanisms until recently. Dr. Serhan’s work has shown that there is an organized progression to homeostasis from…

1. Insights from the Metagenics Lifestyle Summit 2015 in Phoenix, AZ: Charles Serhan, PhD If already taking fish oils, is there a need to supplement with specialized pro-resolving mediators (SPMs)? In this video, Dr. Charles Serhan presents insights on inflammation from the Metagenics Lifestyle Summit in September 2015. Dr. Serhan is a distinguished researcher and professor at Harvard Medical School and Brigham and Women’s Hospital in Boston, MA. Dr. Serhan cites his research to answer a variety of questions on…

ASPEN 2015 Inflammation: Fish Oils vs SPMs: What's the Difference? - 1 Roundtable Symposia from ASPEN Clinical Nutrition Week 2015 Participating Speakers are: Robert G. Martindale, MD, PhD Stephen McClave, MD Jesmond Dalli, PhD Todd Rice, MD ASPEN Clinical Nutrition Week in February 2015 provided an excellent opportunity for experts in clinical nutrition to gather and discuss new clinical science from the field. In a series of discussions on Inflammation, Dr. Robert Martindale moderates conversation among several experts, including…

This animation features information on the role of inflammation in managing insults and injury to the body. Infection, wounds, poor diet, and aging are causes of acute inflammation. Acute inflammation helps the body to heal and helps tissue to return to homeostasis. When inflammation becomes chronic, however, as is common in many chronic diseases, it can destroy tissues and leave the body in poorer health. Science has now shown us that inflammation resolution is an active process that is controlled by specialized pro-resolving mediators (SPMs),…

What do we know about hormones for menopause? What are the risks and the benefits for women? Erika Schwartz, MD Chief Medical Officer at the Age Management Institute discusses the state of science and uses of hormone therapy for health concerns and improving quality of life. Dr. Schwartz also discusses the importance of preventative and individualized medicine for women. Presented at the Integrative Healthcare Symposium Annual Conference (IHS) in New York City – February 22, 2017 View the slides  …

Hypertension (HTN) affects more than a third (32.6%) of Americans and is a major risk factor for heart disease and mortality.1 Unfortunately, the exact mechanisms as to development and maintenance of this condition are yet to be understood. It has been suggested that HTN is associated with a fundamental defect in the ability for the kidneys to excrete sodium.2 Salt sensitivity of blood pressure (BP) is a measurable, physiological, trait where an increase in dietary sodium intake leads to an increase in…

Clinicians and healthcare practitioners have a unique opportunity in advocating lifestyle medicine because patients see them as a reliable source of advice. However, there are still numerous technical and logistic challenges to overcome before personal “big data” can be translated into actionable and clinically relevant solutions. Clinicians are also facing various issues prior to bringing personalized lifestyle medicine to their practice. Nevertheless, emerging ground-breaking research projects have given us a glimpse of how systems thinking and computational methods may lead…

During periods of over-nutrition, excess energy is stored in white adipose tissue (WAT); continuing expansion of WAT may lead to obesity. Obesity alters the cellular physiology of adipocytes, the cells of WAT. In the context of obesity, adipocytes secrete elevated levels of free fatty acids and adipokines, but decreased levels of adiponectin. These pathophysiologic changes have many effects. Elevated free fatty acids contribute to insulin resistance, oxidative stress, inflammation, and impaired arterial flow regulation Download the PDF

The clinical results of a randomized controlled research study that showed a diabetes-specific nutrition formula for glucose control in combination with a structured dietary plan resulted in significant reduction in HbA1c levels and body weight in overweight and obese patients with type 2 diabetes (T2D) compared to an individualized dietary plan alone. The study, conducted by the Joslin Diabetes Center, was presented at the American Diabetes Association’s 76th Scientific Sessions in New Orleans, Louisiana. "Effective management of A1c levels, while challenging, is…

This research review discusses how the combination of undenatured type II collagen and tetrahydro iso-alpha acids help revitalize joint function and support an active lifestyle. Arthritis is not a single condition. In fact, there are more than 100 different forms of arthritis. The 2 most common types of arthritis, whose main feature is joint pain, are osteoarthritis (OA) and rheumatoid arthritis (RA). OA is a degenerative joint disease characterized by active bone remodeling, articular cartilage degradation, and synovial inflammation resulting…